[HTML][HTML] Asymmetric organocatalysis: an enabling technology for medicinal chemistry

B Han, XH He, YQ Liu, G He, C Peng… - Chemical Society Reviews, 2021 - pubs.rsc.org
The efficacy and synthetic versatility of asymmetric organocatalysis have contributed
enormously to the field of organic synthesis since the early 2000s. As asymmetric …

A review: Mechanism of action of antiviral drugs

S Kausar, F Said Khan… - International journal …, 2021 - journals.sagepub.com
Antiviral drugs are a class of medicines particularly used for the treatment of viral infections.
Drugs that combat viral infections are called antiviral drugs. Viruses are among the major …

Impact of obesity on influenza A virus pathogenesis, immune response, and evolution

R Honce, S Schultz-Cherry - Frontiers in immunology, 2019 - frontiersin.org
With the rising prevalence of obesity has come an increasing awareness of its impact on
communicable disease. As a consequence of the 2009 H1N1 influenza A virus pandemic …

Medicinal chemistry strategies for discovering antivirals effective against drug-resistant viruses

Y Ma, E Frutos-Beltrán, D Kang… - Chemical Society …, 2021 - pubs.rsc.org
During the last forty years we have witnessed impressive advances in the field of antiviral
drug discovery culminating with the introduction of therapies able to stop human …

Harnessing microalgae as sustainable cellular factories for biopharmaceutical production

H Goshtasbi, YB Okolodkov, A Movafeghi, S Awale… - Algal research, 2023 - Elsevier
The biotechnology sector centered around microalgae is experiencing a remarkable surge
in growth. So far, over 300,000 distinct species of microalgae have been meticulously …

A review of the antiviral activity of cationic antimicrobial peptides

UL Urmi, AK Vijay, R Kuppusamy, S Islam… - Peptides, 2023 - Elsevier
Viral epidemics are occurring frequently, and the COVID-19 viral pandemic has resulted in
at least 6.5 million deaths worldwide. Although antiviral therapeutics are available, these …

Integrating molecular modelling methods to advance influenza A virus drug discovery

H Patel, A Kukol - Drug discovery today, 2021 - Elsevier
Highlights•No new influenza A antivirals have gained global approval for nearly two
decades.•Due to influenza A evolution more antiviral options are needed.•Promising anti …

Antiviral activities and applications of ribosomally synthesized and post-translationally modified peptides (RiPPs)

Y Fu, AH Jaarsma, OP Kuipers - Cellular and Molecular Life Sciences, 2021 - Springer
The emergence and re-emergence of viral epidemics and the risks of antiviral drug
resistance are a serious threat to global public health. New options to supplement or replace …

Antiviral fungal metabolites and some insights into their contribution to the current COVID-19 pandemic

JA Takahashi, BVR Barbosa, MTNS Lima… - Bioorganic & Medicinal …, 2021 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak, which
started in late 2019, drove the scientific community to conduct innovative research to contain …

[HTML][HTML] Potential molecular targets of nonstructural proteins for the development of antiviral drugs against SARS-CoV-2 infection

X Liu, X Zhang, Z Lu, Y Zhu, T Wang - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Outbreaks of severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East
respiratory syndrome coronavirus (MERS-CoV), and SARS-CoV-2 have produced high …