In the final steps of energy conservation in aerobic organisms, free energy from electron
transfer through the respiratory chain is transduced into a proton electrochemical gradient …

Mitochondria are the power stations of the eukaryotic cell, using the energy released by the
oxidation of glucose and other sugars to produce ATP. Electrons are transferred from NADH …

Cytochrome c oxidase (complex IV, CIV) is known in mammals to exist independently or in
association with other respiratory proteins to form supercomplexes (SCs). In Saccharomyces …

Respiratory chain complexes execute energy conversion by connecting electron transport
with proton translocation over the inner mitochondrial membrane to fuel ATP synthesis …

Protein cross-linking and the analysis of cross-linked peptides by mass spectrometry is
currently receiving much attention. Not only is this approach applied to isolated complexes …

Fission yeast Schizosaccharomyces pombe serves as model organism for studying higher
eukaryotes. We combined the use of cryo-EM and spectroscopy to investigate the structure …

The correct targeting and insertion of tail‐anchored (TA) integral membrane proteins is
critical for cellular homeostasis. TA proteins are defined by a hydrophobic transmembrane …

The respiratory pathway of mitochondria is composed of four electron transfer complexes
and the ATP synthase. In this article, we review evidence from studies of Saccharomyces …

The functional and structural relationship among the individual components of the
mitochondrial respiratory chain constitutes a central aspect of our understanding of aerobic …

Cytochrome c oxidase (CcO) is the last electron acceptor in the respiratory chain. The CcO
core is formed by mitochondrial DNA-encoded Cox1, Cox2, and Cox3 subunits. Cox1 …