[HTML][HTML] Cyclodextrins: Structural, chemical, and physical properties, and applications
Due to their unique structural, physical and chemical properties, cyclodextrins and their
derivatives have been of great interest to scientists and researchers in both academia and …
derivatives have been of great interest to scientists and researchers in both academia and …
Overview of nanoparticulate strategies for solubility enhancement of poorly soluble drugs
KU Khan, MU Minhas, SF Badshah, M Suhail, A Ahmad… - Life Sciences, 2022 - Elsevier
Poor aqueous solubility and poor bioavailability are major issues with many pharmaceutical
industries. By some estimation, 70–90% drug candidates in development stage while up-to …
industries. By some estimation, 70–90% drug candidates in development stage while up-to …
[HTML][HTML] Intestinal absorption study: Challenges and absorption enhancement strategies in improving oral drug delivery
M Azman, AH Sabri, QK Anjani, MF Mustaffa… - Pharmaceuticals, 2022 - mdpi.com
The oral route is the most common and practical means of drug administration, particularly
from a patient's perspective. However, the pharmacokinetic profile of oral drugs depends on …
from a patient's perspective. However, the pharmacokinetic profile of oral drugs depends on …
[HTML][HTML] Pharmaceutical particle technologies: An approach to improve drug solubility, dissolution and bioavailability
P Khadka, J Ro, H Kim, I Kim, JT Kim, H Kim… - Asian journal of …, 2014 - Elsevier
Pharmaceutical particle technology is employed to improve poor aqueous solubility of drug
compounds that limits in vivo bioavailability owing to their low dissolution rate in the …
compounds that limits in vivo bioavailability owing to their low dissolution rate in the …
Cyclodextrins as encapsulation agents for plant bioactive compounds
Plants possess a wide range of molecules capable of improve healing: fibre, vitamins,
phytosterols, and further sulphur-containing compounds, carotenoids, organic acid anions …
phytosterols, and further sulphur-containing compounds, carotenoids, organic acid anions …
A comprehensive review on contact lens for ophthalmic drug delivery
J Xu, Y Xue, G Hu, T Lin, J Gou, T Yin, H He… - Journal of controlled …, 2018 - Elsevier
With the prevalence of electronic devices and an aging population, the number of people
affected with eye disease is increasing year by year. In spite of a large number of eye drops …
affected with eye disease is increasing year by year. In spite of a large number of eye drops …
Co-delivery of siRNA and therapeutic agents using nanocarriers to overcome cancer resistance
M Creixell, NA Peppas - Nano today, 2012 - Elsevier
There are two main mechanisms by which cells become multidrug resistant (MDR): by
increasing drug efflux pumps on the cell membrane and by increasing anti-apoptotic …
increasing drug efflux pumps on the cell membrane and by increasing anti-apoptotic …
Nanosponges: A novel class of drug delivery system-review
S Selvamuthukumar, S Anandam… - … of Pharmacy & …, 2012 - journals.library.ualberta.ca
Effective targeted drug delivery systems have been a dream for a long time, but it has been
largely frustrated by the complex chemistry that is involved in the development of new …
largely frustrated by the complex chemistry that is involved in the development of new …
Exploring versatile applications of cyclodextrins: an overview
N Sharma, A Baldi - Drug delivery, 2016 - Taylor & Francis
Context: Ever since the discovery of cyclodextrins, a family of cyclic oligosaccharides based
on α (1→ 4) linkage among glucopyranose subunits, these versatile supramolecular hosts …
on α (1→ 4) linkage among glucopyranose subunits, these versatile supramolecular hosts …
[HTML][HTML] Cyclodextrin inclusion complexes for improved drug bioavailability and activity: synthetic and analytical aspects
Many active pharmaceutical ingredients show low oral bioavailability due to factors such as
poor solubility and physical and chemical instability. The formation of inclusion complexes …
poor solubility and physical and chemical instability. The formation of inclusion complexes …