Review on the computational genome annotation of sequences obtained by next-generation sequencing
GF Ejigu, J Jung - Biology, 2020 - mdpi.com
Simple Summary Due to the development of high-throughput sequencing technologies,
computational genome annotation of sequences has become one of the principal research …
computational genome annotation of sequences has become one of the principal research …
PVT1: a rising star among oncogenic long noncoding RNAs
It is becoming increasingly clear that short and long noncoding RNAs critically participate in
the regulation of cell growth, differentiation, and (mis) function. However, while the functional …
the regulation of cell growth, differentiation, and (mis) function. However, while the functional …
The EMBL-EBI bioinformatics web and programmatic tools framework
Abstract Since 2009 the EMBL-EBI Job Dispatcher framework has provided free access to a
range of mainstream sequence analysis applications. These include sequence similarity …
range of mainstream sequence analysis applications. These include sequence similarity …
MG-RAST, a metagenomics service for analysis of microbial community structure and function
Approaches in molecular biology, particularly those that deal with high-throughput
sequencing of entire microbial communities (the field of metagenomics), are rapidly …
sequencing of entire microbial communities (the field of metagenomics), are rapidly …
NCBI viral genomes resource
JR Brister, D Ako-Adjei, Y Bao… - Nucleic acids …, 2015 - academic.oup.com
Recent technological innovations have ignited an explosion in virus genome sequencing
that promises to fundamentally alter our understanding of viral biology and profoundly …
that promises to fundamentally alter our understanding of viral biology and profoundly …
Long noncoding RNAs in cancer: from discovery to therapeutic targets
R Choudhari, MJ Sedano, AL Harrison… - Advances in clinical …, 2020 - Elsevier
Long noncoding RNAs (lncRNAs) have recently gained considerable attention as key
players in biological regulation; however, the mechanisms by which lncRNAs govern …
players in biological regulation; however, the mechanisms by which lncRNAs govern …
The European Bioinformatics Institute in 2016: data growth and integration
New technologies are revolutionising biological research and its applications by making it
easier and cheaper to generate ever-greater volumes and types of data. In response, the …
easier and cheaper to generate ever-greater volumes and types of data. In response, the …
DeepDSC: a deep learning method to predict drug sensitivity of cancer cell lines
High-throughput screening technologies have provided a large amount of drug sensitivity
data for a panel of cancer cell lines and hundreds of compounds. Computational …
data for a panel of cancer cell lines and hundreds of compounds. Computational …
Problems, challenges and promises: perspectives on precision medicine
DJ Duffy - Briefings in bioinformatics, 2016 - academic.oup.com
The 'precision medicine (systems medicine)'concept promises to achieve a shift to future
healthcare systems with a more proactive and predictive approach to medicine, where the …
healthcare systems with a more proactive and predictive approach to medicine, where the …
Biological databases for human research
The completion of the Human Genome Project lays a foundation for systematically studying
the human genome from evolutionary history to precision medicine against diseases. With …
the human genome from evolutionary history to precision medicine against diseases. With …