Sex differences in cancer mechanisms

JB Rubin, JS Lagas, L Broestl, J Sponagel… - Biology of sex …, 2020 - Springer
We now know that cancer is many different diseases, with great variation even within a
single histological subtype. With the current emphasis on developing personalized …

From carcinogenesis to therapeutic avenues: lncRNAs and mTOR crosstalk in lung cancer

MS Hussain, ASA Altamimi, M Afzal, I Kazmi… - … -Research and Practice, 2023 - Elsevier
Long non-coding RNAs (lncRNAs) have been demonstrated to have a crucial function in the
modulation of the activity of genes, impacting a variety of homeostatic processes involving …

lncRNA JPX/miR-33a-5p/Twist1 axis regulates tumorigenesis and metastasis of lung cancer by activating Wnt/β-catenin signaling

J Pan, S Fang, H Tian, C Zhou, X Zhao, H Tian, J He… - Molecular cancer, 2020 - Springer
Abstract Background MicroRNAs (miRNAs) and Twist1-induced epithelial-mesenchymal
transition (EMT) in cancer cell dissemination are well established, but the involvement of …

LncRNAs in non-small-cell lung cancer

L Ginn, L Shi, M La Montagna, M Garofalo - Non-coding RNA, 2020 - mdpi.com
Lung cancer is associated with a high mortality, with around 1.8 million deaths worldwide in
2018. Non-small-cell lung cancer (NSCLC) accounts for around 85% of cases and, despite …

EpiFactors 2022: expansion and enhancement of a curated database of human epigenetic factors and complexes

D Marakulina, IE Vorontsov, IV Kulakovskiy… - Nucleic Acids …, 2023 - academic.oup.com
We present an update of EpiFactors, a manually curated database providing information
about epigenetic regulators, their complexes, targets, and products which is openly …

Long non-coding RNAs as new players in bladder cancer: Lessons from pre-clinical and clinical studies

S Mirzaei, MDA Paskeh, F Hashemi, A Zabolian… - Life Sciences, 2022 - Elsevier
The clinical management of bladder cancer (BC) has become an increasing challenge due
to high incidence rate of BC, malignant behavior of cancer cells and drug resistance. The …

[HTML][HTML] The role of selected non-coding RNAs in the biology of non-small cell lung cancer

K Kiełbowski, K Ptaszyński, J Wojcik… - Advances in Medical …, 2023 - Elsevier
Lung cancer is the second most frequently diagnosed cancer worldwide and a leading
cause of cancer-related deaths. Non-small cell lung carcinoma (NSCLC) represents 85% of …

MiR-145-5p suppresses the proliferation, migration and invasion of gastric cancer epithelial cells via the ANGPT2/NOD_LIKE_RECEPTOR axis

K Zhou, B Song, M Wei, J Fang, Y Xu - Cancer Cell International, 2020 - Springer
Objective This study aimed to investigate the relationship among miR-145-5p, ANGPT2 and
the NOD_LIKE_RECEPTOR pathway, thereby revealing the molecular mechanism of these …

[HTML][HTML] Epigenetic regulation of autophagy by non-coding RNAs in gastrointestinal tumors: Biological functions and therapeutic perspectives

MA Zandieh, MH Farahani, R Rajabi, ST Avval… - Pharmacological …, 2023 - Elsevier
Cancer is the manifestation of changes and mutations in genetic and epigenetic levels. Non-
coding RNAs (ncRNAs) are commonly dysregulated in disease pathogenesis, and their role …

Anticancer effects of melatonin via regulating lncRNA JPX‐Wnt/β‐catenin signalling pathway in human osteosarcoma cells

Y Li, J Zou, B Li, J Du - Journal of Cellular and Molecular …, 2021 - Wiley Online Library
Osteosarcoma (OS) is a type of malignant primary bone cancer, which is highly aggressive
and occurs more commonly in children and adolescents. Thus, novel potential drugs and …