The noradrenergic theory of Cognitive Reserve (Robertson, 2013–2014) postulates that the
upregulation of the locus coeruleus—noradrenergic system (LC–NA) originating in the …

BACKGROUND: The utility of neuropsychology in the treatment and evaluation of
neuropsychological disorders and neurodegenerative diseases is supported by scientific …

Kognitiivinen ikääntyminen kuuluu läpi elämän tapahtuviin muutoksiin muistissa ja muissa
tiedon käsittelyyn liittyvissä toiminnoissa. Monet kognition osaalueet alkavat heiketä jo …

Abstract Introduction Practice effects (PEs) on cognitive tests obscure decline, thereby
delaying detection of mild cognitive impairment (MCI). Importantly, PEs may be present even …

The efficacy of donepezil is well known for improving the cognitive performance in patients
with mild cognitive impairment (MCI) and Alzheimer's disease (AD). Most of the recent …

Background Screening procedures for early Alzheimer's disease (AD) trials seek to
efficiently identify participants who fulfill clinical and biomarker criteria for AD and enrich for …

The relationship between hippocampal subfield volumetry and verbal list‐learning test
outcomes have mostly been studied in clinical and elderly populations, and remain …

An efficient method to identify whether mild cognitive impairment (MCI) has progressed to
Alzheimer's disease (AD) will be beneficial to patient care. Previous studies have shown that …

Quantifying the intracranial tissue volume changes in magnetic resonance imaging (MRI)
assists specialists to analyze the effects of natural or pathological changes. Since these …

Background Apolipoprotein E (APOE) ε2 is a protective genetic factor for Alzheimer's
disease (AD). However, the potential interaction effects between the APOE ε2 allele and …