Implant infections: adhesion, biofilm formation and immune evasion

CR Arciola, D Campoccia, L Montanaro - Nature reviews microbiology, 2018 - nature.com
Medical device-associated infections account for a large proportion of hospital-acquired
infections. A variety of opportunistic pathogens can cause implant infections, depending on …

Risk factors and treatment options for failure of a two-stage exchange

L Fagotti, J Tatka, MJC Salles, MC Queiroz - Current reviews in …, 2018 - Springer
Abstract Purpose of Review Although a two-stage exchange revision is reported to have a
high success rate, this strategy may fail as a treatment for prosthetic joint infection (PJI) …

Diagnostic accuracy of MRI with metal artifact reduction for the detection of periprosthetic joint infection and aseptic loosening of total hip arthroplasty

BJ Schwaiger, FT Gassert, C Suren, AS Gersing… - European Journal of …, 2020 - Elsevier
Purpose To evaluate imaging characteristics obtained from magnetic resonance imaging
(MRI) with metal artifact reduction (MAR) to differentiate between periprosthetic joint …

Biodistribution, biocompatibility and targeted accumulation of magnetic nanoporous silica nanoparticles as drug carrier in orthopedics

HC Janßen, N Angrisani, S Kalies, F Hansmann… - Journal of …, 2020 - Springer
Background In orthopedics, the treatment of implant-associated infections represents a high
challenge. Especially, potent antibacterial effects at implant surfaces can only be achieved …

Improved pre-operative diagnostic accuracy for low-grade prosthetic joint infections using second-generation multiplex Polymerase chain reaction on joint fluid …

C Suren, S Feihl, S Cabric, IJ Banke, B Haller… - International …, 2020 - Springer
Background A major obstacle for the treatment of prosthetic joint infection (PJI) is the
identification of the underlying causative organism. While the diagnostic criteria ruling PJI in …

Diagnostic accuracy of multiplex polymerase chain reaction on tissue biopsies in periprosthetic joint infections

I Lazic, S Feihl, PM Prodinger, IJ Banke, A Trampuz… - Scientific Reports, 2021 - nature.com
The diagnosis and treatment of periprosthetic joint infection (PJI) currently relies on cultures,
which are time-consuming and often fail. Multiplex PCR assays promise reliable and prompt …

Optimal management of mesh infection: evidence and treatment options

MR Arnold, AM Kao, KK Gbozah… - … Journal of Abdominal …, 2018 - journals.lww.com
Mesh reinforcement is generally considered the standard of care in ventral hernia repair.
Infection is a common complication following ventral hernia repair. Infection extending to the …

One-stage exchange with antibacterial hydrogel coated implants provides similar results to two-stage revision, without the coating, for the treatment of peri-prosthetic …

N Capuano, N Logoluso, E Gallazzi, L Drago… - Knee Surgery, Sports …, 2018 - Springer
Purpose Aim of this study was to verify the hypothesis that a one-stage exchange procedure,
performed with an antibiotic-loaded, fast-resorbable hydrogel coating, provides similar …

Usefulness of a multiplex PCR assay for the diagnosis of prosthetic joint infections in the routine setting

Á Auñón, I Coifman, A Blanco… - Orthopaedic …, 2022 - Wiley Online Library
Objective To evaluate the usefulness of a multiplex polymerase chain reaction (PCR) assay
as a complementary tool in the diagnosis of prosthetic joint infections in the routine setting of …

Insufficient sensitivity of joint aspiration during the two-stage exchange of the hip with spacers

SP Boelch, M Weissenberger, F Spohn… - Journal of Orthopaedic …, 2018 - Springer
Background Evaluation of infection persistence during the two-stage exchange of the hip is
challenging. Joint aspiration before reconstruction is supposed to rule out infection …