The poor aqueous solubility of many approved drugs and most new chemical entities poses
a challenge to drug delivery scientists working in academic and industrial labs. Despite the …

Emerging cancer cases across the globe and treating them with conventional therapies with
multiple limitations have been challenging for decades. Novel drug delivery systems and …

Nintedanib (NIN) and pirfenidone are the only approved drugs for the treatment of Idiopathic
Pulmonary Fibrosis (IPF). However, NIN and pirfenidone have low oral bioavailability and …

Nintedanib (NIN) is one of the FDA-approved tyrosine kinase inhibitor drugs used to treat
idiopathic pulmonary fibrosis (IPF). This study aimed to formulate a long-circulating injection …

Herein, a novel designed antimicrobial therapeutic drug delivery system is presented, in
which halloysite nanotubes (HNTs) encapsulate a determined dosage of levofloxacin (lvx) …

Spray drying is an increasingly used particle engineering technique for the production of dry
powders for inhalation. However, the amorphous nature of most spray-dried particles …

The present work reviews the liquid antisolvent crystallization (LASC) to prepare the
nanoparticle of pharmaceutical compounds to enhance their solubility, dissolution rate, and …

The most favored approach for drug administration is the oral route. Several anticancer
drugs come under this category and mostly lack solubility and oral bioavailability, which are …

The low solubility and bioavailability of aqueous insoluble drugs are critical challenges in
the field of pharmaceuticals that need to be overcome. Nanocrystal technology, a novel …

The pH–induced crystallization of weakly basic drugs in the small intestine limits oral
bioavailability. In this study, we investigated the solubilization and inhibitory effects on …