Neurotrophic basis to the pathogenesis of depression and phytotherapy

H Wang, Y Yang, G Pei, Z Wang, N Chen - Frontiers in Pharmacology, 2023 - frontiersin.org
Depression is a major neuropsychiatric disease that considerably impacts individuals'
psychosocial function and life quality. Neurotrophic factors are now connected to the …

Regulatory mechanism and therapeutic potentials of naringin against inflammatory disorders

Y Peng, R Qu, S Xu, H Bi, D Guo - Heliyon, 2024 - cell.com
Naringin is a natural flavonoid with therapeutic properties found in citrus fruits and an active
natural product from herbal plants. Naringin has become a focus of attention in recent years …

Implication of Wnt/GSK-3β/β-catenin signaling in the pathogenesis of mood disturbances associated with hyperthyroidism in rats: potential therapeutic effect of …

MA Abd-Elmawla, RM Essam, KA Ahmed… - ACS Chemical …, 2023 - ACS Publications
Patients with hyperthyroidism are commonly diagnosed with mood disorders. Naringin,(4′,
5, 7-trihydrocyflavanone-7-O-rhamnoglucoside), a natural bioflavonoid, has many …

[HTML][HTML] Chronic exposure to aflatoxin B1 increases hippocampal microglial pyroptosis and vulnerability to stress in mice

D Su, W Jiang, Q Yuan, L Guo, Q Liu, M Zhang… - Ecotoxicology and …, 2023 - Elsevier
Abstract Background Chronic aflatoxin B1 (AFB1) exposure may increase the risk of multiple
neuropsychiatric disorders. Stress is considered one of the main contributors to major …

Psychopharmacological interaction of alcohol and posttraumatic stress disorder: Effective action of naringin

B Ben-Azu, B Oritsemuelebi, AM Oghorodi… - European Journal of …, 2024 - Elsevier
Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) are prevalently co-
occurring, important risk factors for a broad array of neuropsychiatric diseases. To date, how …

Effect of 2-Week Naringin Supplementation on Neurogenesis and BDNF Levels in Ischemia–Reperfusion Model of Rats

E Yilmaz, G Acar, U Onal, E Erdogan, AK Baltaci… - NeuroMolecular …, 2024 - Springer
Background: Ischemic stroke is the leading cause of mortality and disability worldwide with
more than half of survivors living with serious neurological sequelae; thus, it has recently …

[HTML][HTML] Camellia nitidissima Chi extract promotes adult hippocampal neurogenesis and attenuates chronic corticosterone-induced depressive behaviours through …

B Tsoi, C Gao, S Yan, Q Du, H Yu, P Li, J Deng… - Journal of Functional …, 2022 - Elsevier
Hormonal imbalance causes depressive behaviours in chronic mental disorders. The use of
natural products to relieve depressive symptoms is getting attention due to its minimal side …

Low-dose curcumin enhances hippocampal neurogenesis and memory retention in young mice

Y Lee, HR Park, JY Lee, J Kim, S Yang, C Lee… - Archives of Pharmacal …, 2023 - Springer
Adult neurogenesis generates new functional neurons from adult neural stem cells in
various regions, including the subventricular zone (SVZ) of the lateral ventricles and …

Niuhuang Qingxin Wan ameliorates depressive-like behaviors and improves hippocampal neurogenesis through modulating TrkB/ERK/CREB signaling pathway in …

Q Du, C Gao, B Tsoi, M Wu, J Shen - Frontiers in Pharmacology, 2024 - frontiersin.org
Introduction: Chronic stress-associated hormonal imbalance impairs hippocampal
neurogenesis, contributing to depressive and anxiety behaviors. Targeting neurogenesis is …

The impact of flavonoids and BDNF on neurogenic process in various physiological/pathological conditions including ischemic insults: a narrative review

E Yılmaz, SB Baltaci, R Mogulkoc… - Nutritional …, 2023 - Taylor & Francis
Objective Ischemic stroke is the leading cause of mortality and disability worldwide with
more than half of survivors living with serious neurological sequelae thus, it has recently …