Self-nanoemulsifying drug delivery systems: formulation insights, applications and advances

AA Date, N Desai, R Dixit, M Nagarsenker - Nanomedicine, 2010 - Taylor & Francis
There has been a resurgence of interest in nanoemulsions for various pharmaceutical
applications since low-energy emulsification methods, such as spontaneous or self …

Crystals and crystallization in oil-in-water emulsions: Implications for emulsion-based delivery systems

DJ McClements - Advances in colloid and interface science, 2012 - Elsevier
Many bioactive components intended for oral ingestion (pharmaceuticals and
nutraceuticals) are hydrophobic molecules with low water-solubilities and high melting …

Fabrication of vitamin E-enriched nanoemulsions: Factors affecting particle size using spontaneous emulsification

AH Saberi, Y Fang, DJ McClements - Journal of colloid and interface …, 2013 - Elsevier
Oil-in-water nanoemulsions are finding increasing use as delivery systems to encapsulate
lipophilic bioactive components in functional food, personal care, and pharmaceutical …

Plant-based antidiabetic nanoformulations: the emerging paradigm for effective therapy

S Dewanjee, P Chakraborty, B Mukherjee… - International journal of …, 2020 - mdpi.com
Diabetes mellitus is a life-threatening metabolic syndrome. Over the past few decades, the
incidence of diabetes has climbed exponentially. Several therapeutic approaches have …

Nanoemulsion-based delivery systems for poorly water-soluble bioactive compounds: Influence of formulation parameters on polymethoxyflavone crystallization

Y Li, J Zheng, H Xiao, DJ McClements - Food hydrocolloids, 2012 - Elsevier
Polymethoxyflavones (PMFs) extracted from citrus peel exhibit potent anti-cancer activity, but
are highly hydrophobic molecules with poor solubility in both water and oil at ambient and …

Effect of glycerol on formation, stability, and properties of vitamin-E enriched nanoemulsions produced using spontaneous emulsification

AH Saberi, Y Fang, DJ McClements - Journal of colloid and interface …, 2013 - Elsevier
Oil-in-water nanoemulsions are finding increasing use as delivery systems to encapsulate
lipophilic bioactive components in functional food, personal care, and pharmaceutical …

Self-nano emulsifying drug delivery system (SNEDDS): future aspects

HA Makadia, AY Bhatt, RB Parmar… - Asian Journal of …, 2013 - indianjournals.com
Oral route is the easiest and most convenient route for drug administration. more than 40%
of new chemical entities exhibit poor aqueous solubility, resulting in unsatisfactory oral drug …

Potentials and challenges in self-nanoemulsifying drug delivery systems

AW Khan, S Kotta, SH Ansari… - Expert opinion on drug …, 2012 - Taylor & Francis
Introduction: A significant number of new chemical entities (almost 40%), that are outcome of
contemporary drug discovery programs, have a potential therapeutic promise for patient, as …

Nanoscale delivery systems of lutein: An updated review from a pharmaceutical perspective

AH Algan, A Gungor-Ak, A Karatas - Pharmaceutics, 2022 - mdpi.com
Carotenoids are natural lipid-soluble pigments that produce yellow to red colors in plants as
well as providing bright coloration in vegetables and fruits. Lutein belongs to the xanthophyll …

Solid self-nanoemulsifying drug delivery system (S-SNEDDS) containing phosphatidylcholine for enhanced bioavailability of highly lipophilic bioactive carotenoid …

S Shanmugam, R Baskaran, P Balakrishnan… - European Journal of …, 2011 - Elsevier
The objectives of this study was to prepare solid self-nanoemulsifying drug delivery system
(S-SNEDDS) containing phosphatidylcholine (PC), an endogenous phospholipid with …