A comprehensive analysis and anti-cancer activities of quercetin in ROS-mediated cancer and cancer stem cells
Reactive oxygen species (ROS) induce carcinogenesis by causing genetic mutations,
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …
[HTML][HTML] Advanced implications of nanotechnology in disease control and environmental perspectives
Nanotechnology encompasses a wide range of devices derived from biology, engineering,
chemistry, and physics, and this scientific field is composed of great collaboration among …
chemistry, and physics, and this scientific field is composed of great collaboration among …
Oncoinformatic screening of the gene clusters involved in the HER2-positive breast cancer formation along with the in silico pharmacodynamic profiling of selective …
The HER2-positive patients occupy~ 30% of the total breast cancer patients globally where
no prevalent drugs are available to mitigate the frequent metastasis clinically except …
no prevalent drugs are available to mitigate the frequent metastasis clinically except …
[HTML][HTML] Point-specific interactions of isovitexin with the neighboring amino acid residues of the hACE2 receptor as a targeted therapeutic agent in suppressing the …
Objective: Despite the development of several vaccines against severe acute respiratory
syndrome coronavirus-2, the need for an additional prophylactic agent is evident. In recent …
syndrome coronavirus-2, the need for an additional prophylactic agent is evident. In recent …
Natural flavonoids effectively block the CD81 receptor of hepatocytes and inhibit HCV infection: A computational drug development approach
Hepatitis C virus (HCV) infection is a major public health concern, and almost two million
people are infected per year globally. This is occurred by the diverse spectrum of viral …
people are infected per year globally. This is occurred by the diverse spectrum of viral …
Revolutionizing anti-cancer drug discovery against breast cancer and lung cancer by modification of natural genistein: an advanced computational and drug design …
Breast and lung cancer are two of the most lethal forms of cancer, responsible for a
disproportionately high number of deaths worldwide. Both doctors and cancer patients …
disproportionately high number of deaths worldwide. Both doctors and cancer patients …
Target-specificity of different amyrin subunits in impeding HCV influx mechanism inside the human cells considering the quantum tunnel profiles and molecular strings …
HCV is a hepatotropic RNA virus recognized for its frequent virulence and fatality worldwide.
Despite many vaccine development programs underway, researchers are on a quest for …
Despite many vaccine development programs underway, researchers are on a quest for …
Study of MDM2 as Prognostic Biomarker in Brain-LGG Cancer and Bioactive Phytochemicals Inhibit the p53-MDM2 Pathway: A Computational Drug Development …
An evaluation of the expression and predictive significance of the MDM2 gene in brain lower-
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
[HTML][HTML] Novel compounds from endophytic fungi of Ceriops decandra inhibit breast cancer cell growth through estrogen receptor alpha in in-silico study
Endophytic fungi can thrive without producing illness or injury to the host plant tissues, and
they are also one of the major natural sources of bioactive compounds. The objective of the …
they are also one of the major natural sources of bioactive compounds. The objective of the …
Molecular Dynamics Simulation and Pharmacoinformatic Integrated Analysis of Bioactive Phytochemicals from Azadirachta indica (Neem) to Treat Diabetes Mellitus
A Abdullah, P Biswas, M Sahabuddin… - Journal of …, 2023 - Wiley Online Library
Diabetes mellitus is a chronic hormonal and metabolic disorder in which our body cannot
generate necessary insulin or does not act in response to it, accordingly, ensuing in …
generate necessary insulin or does not act in response to it, accordingly, ensuing in …