In recent years, several publications reported that nanoparticles larger than the kidney
filtration threshold were found intact in the urine after being injected into laboratory mice …

Nowadays exploration of novel lipid-based formulations is akin to a magnet for researchers
worldwide for improving the in vivo performance of highly lipophilic drugs. Over the last few …

The main purpose of this study was to develop a solid self-nanoemulsifying drug delivery
system (S-SNEDDS) of Olmesartan (OLM) for enhancement of its solubility and dissolution …

Oral delivery is the most accepted and economical route for drug administration and leads to
substantial reduction in dosing frequency. However, this route still remains a challenge for …

Mesoporous silica nanocarrier (MSN) preparations have a wide range of medical
applications. Studying the biocompatibility of MSN is an important part of clinical …

Oral drug absorption is a process influenced by the physicochemical and biopharmaceutical
properties of the drug and its inter-relationship with the gastrointestinal tract. Drug solubility …

Over the past few decades, researchers and companies have been trying to develop novel
drug delivery systems to ensure safety, efficacy, compliance, and patient acceptability …

Traditional Chinese medicine (TCM) has been practiced for thousands of years with a recent
increase in popularity. Despite promising biological activities of active ingredients and …

The exploitation of mesoporous silica nanoparticles (MSNs) as drug delivery systems has
grown exponentially due to their remarkable tunable properties, such as high surface area …

Lower doses of capsaicin (8-methyl-N-vanillyl-6-nonenamide) have the potential to serve as
an anticancer drug, however, due to its pungency, irritant effect, poor water solubility and …