Advanced analgesic drug delivery and nanobiotechnology
N Stoicea, J Fiorda-Diaz, N Joseph, M Shabsigh… - Drugs, 2017 - Springer
Transdermal administration of analgesic medications offers several benefits over alternative
routes of administration, including a decreased systemic drug load with fewer side effects …
routes of administration, including a decreased systemic drug load with fewer side effects …
Drug delivery strategies for curcumin and other natural Nrf2 modulators of oxidative stress-related diseases
Oxidative stress is associated with a wide range of diseases characterised by oxidant-
mediated disturbances of various signalling pathways and cellular damage. The only …
mediated disturbances of various signalling pathways and cellular damage. The only …
[图书][B] Nano-and microscale drug delivery systems: Design and fabrication
AM Grumezescu - 2017 - books.google.com
Nano-and Microscale Drug Delivery Systems: Design and Fabrication presents the
developments that have taken place in recent years in the field of micro-and nanoscale drug …
developments that have taken place in recent years in the field of micro-and nanoscale drug …
“Fusion and binding inhibition” key target for HIV-1 treatment and pre-exposure prophylaxis: targets, drug delivery and nanotechnology approaches
More than 35 million people are living with HIV worldwide with approximately 2.3 million
new infections per year. Cascade of events (cell entry, virus replication, assembly and …
new infections per year. Cascade of events (cell entry, virus replication, assembly and …
Pancreatic cancer: Recent advances in nanoformulation-based therapies
P Desai, D Ann, J Wang… - Critical Reviews™ in …, 2019 - dl.begellhouse.com
Pancreatic cancer is the fourth leading cause of death in the United States and has a 5-year
life expectancy of~ 8%. Currently, only a few drugs have been approved by the United …
life expectancy of~ 8%. Currently, only a few drugs have been approved by the United …
A study to enhance the oral bioavailability of s-adenosyl-l-methionine (SAMe): SLN and SLN nanocomposite particles
The endogenous molecule, S-adenosyl-l-methionine (SAMe) is a key factor due to its role in
the methylation cycle and modulation of monoaminergic neurotransmission. Since many …
the methylation cycle and modulation of monoaminergic neurotransmission. Since many …
Unexpected solubility enhancement of drug bases in the presence of a dimethylaminoethyl methacrylate copolymer
W Saal, A Ross, N Wyttenbach, J Alsenz… - Molecular …, 2018 - ACS Publications
The methacrylate copolymer Eudragit EPO (EPO) has previously shown to greatly enhance
solubilization of acidic drugs via ionic interactions and by multiple hydrophobic contacts with …
solubilization of acidic drugs via ionic interactions and by multiple hydrophobic contacts with …
Challenges in oral drug delivery and applications of lipid nanoparticles as potent oral drug carriers for managing cardiovascular risk factors
Background: The oral application of drugs is the most popular route through which the
systemic effect can be achieved. Nevertheless, oral administration is limited by difficulties …
systemic effect can be achieved. Nevertheless, oral administration is limited by difficulties …
Understanding and managing oral bioavailability: physiological concepts and patents
MA Alam, FI Al-Jenoobi… - Recent Patents on Anti …, 2015 - ingentaconnect.com
Oral delivery of poorly bioavailable therapeuticals is challenging. The challenges are more
serious when physiological factors of gut such as cytochrome P450, P-glycoprotein …
serious when physiological factors of gut such as cytochrome P450, P-glycoprotein …
Nanoformulation strategies for the enhanced oral bioavailability of antiretroviral therapeutics
LM Tatham, SP Rannard, A Owen - Therapeutic delivery, 2015 - Taylor & Francis
The oral delivery of drugs with poor aqueous solubility is challenging and often results in
poor bioavailability. Various nanoformulation platforms have demonstrated improved oral …
poor bioavailability. Various nanoformulation platforms have demonstrated improved oral …