An updated overview of cyclodextrin-based drug delivery systems for cancer therapy

DN Păduraru, AG Niculescu, A Bolocan, O Andronic… - Pharmaceutics, 2022 - mdpi.com
Encompassing a group of complex and heterogeneous diseases, cancer continues to be a
challenge for patients and healthcare systems worldwide. Thus, it is of vital importance to …

Obesity and main urologic cancers: Current systematic evidence, novel biological mechanisms, perspectives and challenges

G Papavasileiou, D Tsilingiris, N Spyrou… - Seminars in Cancer …, 2023 - Elsevier
Urologic cancers (UC) account for 13.1% of all new cancer cases and 7.9% of all cancer-
related deaths. A growing body of evidence has indicated a potential causal link between …

Sex differences in renal cell carcinoma: a single-cell analysis reveals exhausted CD8+ T-cells highly infiltrated in males

K Ning, Y Peng, Y Jiang, Z Li, X Luo, L Lin… - Biology of sex …, 2023 - Springer
Background Although sex bias has been reported in the development and progression of
renal cell carcinoma (RCC), the underlying mechanisms remain enigmatic. Here, we …

Epidemiological trends of kidney cancer along with attributable risk factors in China from 1990 to 2019 and its projections until 2030: An analysis of the global burden …

Q Xu, T Zhang, T Xia, B Jin, H Chen… - Clinical Epidemiology, 2023 - Taylor & Francis
Background Understanding the past and future burden of kidney cancer in China over years
provides essential references for optimizing the prevention and management strategies …

[PDF][PDF] Von Hippel Lindau tumor suppressor controls m6A-dependent gene expression in renal tumorigenesis

C Zhang, M Yu, AJ Hepperla, Z Zhang… - Journal of Clinical …, 2024 - Am Soc Clin Investig
N6-Methyladenosine (m6A) is the most abundant posttranscriptional modification, and its
contribution to cancer evolution has recently been appreciated. Renal cancer is the most …

Evolution of the HIF targeted therapy in clear cell renal cell carcinoma

B Golijanin, K Malshy, S Khaleel, G Lagos… - Cancer Treatment …, 2023 - Elsevier
Clear cell renal cell carcinoma (ccRCC) is the most common type of kidney cancer, affecting
hundreds of thousands of people worldwide and can affect people of any age. The …

Dyskerin and telomerase RNA component are sex-differentially associated with outcomes and Sunitinib response in patients with clear cell renal cell carcinoma

H Yuan, X Qin, Q Yang, L Liu, Z Fang, Y Fan… - Biology of Sex …, 2023 - Springer
Background Clear cell renal cell carcinoma (ccRCC) displays sex-biased incidence,
outcomes, molecular alterations and treatment efficacy; however, clinical managements are …

Beyond prostate cancer: An androgen receptor splice variant expression in multiple malignancies, non-cancer pathologies, and development

KD Katleba, PM Ghosh, M Mudryj - Biomedicines, 2023 - mdpi.com
Multiple studies have demonstrated the importance of androgen receptor (AR) splice
variants (SVs) in the progression of prostate cancer to the castration-resistant phenotype …

Global epidemiology of kidney cancer

L Cirillo, S Innocenti, F Becherucci - Nephrology Dialysis …, 2024 - academic.oup.com
Kidney cancer (KC) is a disease with a rising worldwide incidence estimated at 400 000 new
cases annually, and a worldwide mortality rate approaching 175 000 deaths per year …

Development and validation of a nomogram for predicting in-hospital mortality of elderly patients with persistent sepsis-associated acute kidney injury in intensive care …

W Jiang, C Zhang, J Yu, J Shao, R Zheng - BMJ open, 2023 - bmjopen.bmj.com
Objectives To identify the clinical risk factors that influence in-hospital mortality in elderly
patients with persistent sepsis-associated acute kidney injury (S-AKI) and to establish and …