[HTML][HTML] Chinese herbal medicines for the treatment of depression: a systematic review and network meta-analysis

C Dang, Q Wang, Q Li, Y Xiong, Y Lu - Frontiers in Pharmacology, 2024 - frontiersin.org
Objectives: Amidst rising global burden of depression and the associated challenges with
conventional antidepressant therapies, there is a growing interest in exploring the efficacy …

[HTML][HTML] Bioactive Components of Areca Nut: An Overview of Their Positive Impacts Targeting Different Organs

H Sun, W Yu, H Li, X Hu, X Wang - Nutrients, 2024 - mdpi.com
Areca catechu L. is a widely cultivated tropical crop in Southeast Asia, and its fruit, areca nut,
has been consumed as a traditional Chinese medicinal material for more than 10,000 years …

Intranasal Monophosphoryl Lipid a Administration Ameliorates depression-like Behavior in Chronically Stressed Mice Through Stimulation of Microglia

M Zheng, T Zhu, B Chen, H Zhao, X Lu, Q Lu… - Neurochemical …, 2023 - Springer
We and others have reported that systematic stimulation of the central innate immune
system by a low dose of lipopolysaccharide (LPS) can improve depression-like behavior in …

Dopaminergic Modulation and Computational ADMET Insights for the Antidepressant-like Effect of N-(3-(Phenylselanyl)prop-2-yn-1-yl)benzamide

EM Besckow, KNB Ledebuhr, CS Pires… - ACS Chemical …, 2024 - ACS Publications
The compound N-(3-(phenylselanyl) prop-2-yn-1-yl) benzamide (SePB), which combines a
selenium atom and a benzamide nucleus in an organic structure, has demonstrated a fast …

[HTML][HTML] Antidepressant and anxiolytic potential of Citrus reticulata Blanco essential oil: a network pharmacology and animal model study

NP Khanh Nguyen, JH Kwon, MK Kim… - Frontiers in …, 2024 - frontiersin.org
Background: Citrus reticulata Blanco essential oil (CBEO) has attracted increasing attention
as a potential treatment for depression and anxiety in recent years. However, there is limited …

Unlocking new avenues for neuropsychiatric disease therapy: the emerging potential of Peroxisome proliferator-activated receptors as promising therapeutic targets

AD Dey, A Mannan, S Dhiman, TG Singh - Psychopharmacology, 2024 - Springer
Rationale Peroxisome proliferator-activated receptors (PPARs) are transcription factors that
regulate various physiological processes such as inflammation, lipid metabolism, and …

[HTML][HTML] Sub-acute toxicity evaluation of aqueous leaf extract from Passiflora edulis Sims f. edulis (Gulupa) in Wistar rats

A Rodríguez-Usaquén, JJ Sutachan, W Villarreal… - Toxicology Reports, 2023 - Elsevier
Abstract The genus Passiflora (Passifloraceae) comprises about 500 species. The Passiflora
edulis stands out because of its economic and medicinal importance. It is widely planted in …

[HTML][HTML] Does acupuncture treatment modulate inflammatory cytokines in rodent models of depression? A systematic review and meta-analysis

Z Guo, Z Ren, J Yao, Y Li, Z Che, Z Yu… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Background Despite the increasing global prevalence of depression, existing treatment
methods have limitations. Acupuncture has been recognized for its potential to alleviate …

Molecular mechanism of Chang Shen Hua volatile oil modulating brain cAMP-PKA-CREB pathway to improve depression-like behavior in rats

S Zhang, Y Hu, Y Zhao, Y Feng, X Wang, M Miao… - Phytomedicine, 2024 - Elsevier
Background Depression is a common and complex mental illness that manifests as
persistent episodes of sadness, loss of interest, and decreased energy, which might lead to …

[HTML][HTML] Potential Causal Association between Depression and Oral Diseases: A Mendelian Randomization Study

X Zhang, H Jiang, L Zhang, C Li, C Chen, M Xing, Y Ma… - Genes, 2023 - mdpi.com
Background: Globally, oral diseases are common, pose an economic burden, and
significantly decline the quality of life of affected individuals. Recently, researchers have …