Neurobiology of depression in Parkinson's disease: Insights into epidemiology, molecular mechanisms and treatment strategies

MH Ahmad, MA Rizvi, M Ali, AC Mondal - Ageing research reviews, 2023 - Elsevier
Parkinson's disease (PD) is characterized mainly by motor dysfunctions due to the
progressive loss of dopaminergic neurons. However, PD patients experience a multitude of …

Neurotoxicity of e-cigarettes

JA Ruszkiewicz, Z Zhang, FM Gonçalves… - Food and Chemical …, 2020 - Elsevier
It appears that electronic cigarettes (EC) are a less harmful alternative to conventional
cigarette (CC) smoking, as they generate substantially lower levels of harmful carcinogens …

Nicotine and the nicotinic cholinergic system in COVID‐19

Y Tizabi, B Getachew, RL Copeland… - The FEBS …, 2020 - Wiley Online Library
There is an urgent need to address the devastating pandemic, COVID‐19, caused by SARS‐
CoV‐2. The efforts to understand the details of this disease in hope of providing effective …

Nicotinic acetylcholine receptor dysfunction in addiction and in some neurodegenerative and neuropsychiatric diseases

AS Vallés, FJ Barrantes - Cells, 2023 - mdpi.com
The cholinergic system plays an essential role in brain development, physiology, and
pathophysiology. Herein, we review how specific alterations in this system, through genetic …

A systematic review of the antidepressant effects of curcumin: Beyond monoamines theory

JN Matias, G Achete, GSS Campanari… - Australian & New …, 2021 - journals.sagepub.com
Background: Depression is a severe, chronic, and recurring mental health disorder, which
prevalence and morbimortality have increased in recent years. Several theories are …

Novel pharmacotherapies in Parkinson's disease

Y Tizabi, B Getachew, M Aschner - Neurotoxicity Research, 2021 - Springer
Abstract Parkinson's disease (PD), an age-related progressive neurodegenerative condition,
is associated with loss of dopaminergic neurons in the substantia nigra pars compacta …

Nicotinic Acetylcholine Receptors in Glial Cells as Molecular Target for Parkinson's Disease

ÉN Soares, ACS Costa, GJ Ferrolho, RP Ureshino… - Cells, 2024 - mdpi.com
Parkinson's disease (PD) is a progressive neurodegenerative disease characterized by
resting tremor, bradykinesia, rigidity, and postural instability that also includes non-motor …

Butyrate protects against salsolinol-induced toxicity in SH-SY5Y cells: implication for Parkinson's disease

B Getachew, AB Csoka, A Bhatti, RL Copeland… - Neurotoxicity …, 2020 - Springer
Abstract Parkinson's disease (PD), a progressive neurodegenerative disorder, is associated
with the destruction of dopamine neurons in the substantia nigra (SN) and the formation of …

Efficacy of traditional Chinese medicine combined with selective serotonin reuptake inhibitors on the treatment for Parkinson's disease with depression: A systematic …

ST Feng, XL Wang, YT Wang, YH Yuan… - The American Journal …, 2021 - World Scientific
Depression is a common neuropsychiatric symptom of Parkinson's disease (PD), resulting in
a lower quality of life and cognitive impairment in PD patients. Traditional Chinese medicine …

Applications of acupuncture therapy in modulating the plasticity of neurodegenerative disease and depression: do microRNA and neurotrophin BDNF shed light on …

X Li, J Zhao, Z Li, L Zhang, Z Huo - Neural Plasticity, 2020 - Wiley Online Library
As the global population ages, the incidence of neurodegenerative diseases has risen.
Furthermore, it has been suggested that depression, especially in elderly people, may also …