Fifty years on: Serotonin and depression
It has been over 50 years since the original serotonin hypothesis was proposed by the
British Psychiatrist Alec Coppen. Recently, some authors have questioned the validity of the …
British Psychiatrist Alec Coppen. Recently, some authors have questioned the validity of the …
A neurobiological perspective on social influence: Serotonin and social adaptation
P Duerler, FX Vollenweider… - Journal of …, 2022 - Wiley Online Library
Humans are inherently social beings. Being suggestible to each other's expectations
enables pro‐social skills that are crucial for social learning and adaptation. Despite their …
enables pro‐social skills that are crucial for social learning and adaptation. Despite their …
Disordered decision making: a cognitive framework for apathy and impulsivity in huntington's disease
LA Morris, C O'Callaghan, C Le Heron - Movement Disorders, 2022 - Wiley Online Library
A caregiver's all‐too‐familiar narrative‐“He doesn't think through what he does, but mostly
he does nothing.” Apathy and impulsivity, debilitating and poorly understood, commonly co …
he does nothing.” Apathy and impulsivity, debilitating and poorly understood, commonly co …
Anti-depressive-like and cognitive impairment alleviation effects of gastrodia elata Blume water extract is related to gut microbiome remodeling in ApoE−/− mice …
Abstract Ethnopharmacology relevance Gastrodia elata Blume (GE) is a traditional Chinese
dietary therapy used to treat neurological disorders. Gastrodia elata Blume water extract …
dietary therapy used to treat neurological disorders. Gastrodia elata Blume water extract …
Dopaminergic challenge dissociates learning from primary versus secondary sources of information
Some theories of human cultural evolution posit that humans have social-specific learning
mechanisms that are adaptive specialisations moulded by natural selection to cope with the …
mechanisms that are adaptive specialisations moulded by natural selection to cope with the …
Difficult lives explain depression better than broken brains
J Moncrieff, RE Cooper, T Stockmann… - Molecular …, 2024 - nature.com
Human beings are organisms with brains who have emotions and agency. The nature and
size of our brains is what gives us these capacities, but our feelings and our behaviour are …
size of our brains is what gives us these capacities, but our feelings and our behaviour are …
Pathogenesis of depression in Alzheimer's disease
Q Zhan, F Kong, S Shao, B Zhang, S Huang - Neurochemical Research, 2024 - Springer
Depression is a prevalent occurrence among Alzheimer's disease (AD) patients, yet its
underlying mechanism remains unclear. Recent investigations have revealed that several …
underlying mechanism remains unclear. Recent investigations have revealed that several …
[HTML][HTML] Dorsal raphe neurons signal integrated value during multi-attribute decision-making
YY Feng, ES Bromberg-Martin, IE Monosov - bioRxiv, 2023 - ncbi.nlm.nih.gov
The dorsal raphe nucleus (DRN) is implicated in psychiatric disorders that feature impaired
sensitivity to reward amount, impulsivity when facing reward delays, and risk-seeking when …
sensitivity to reward amount, impulsivity when facing reward delays, and risk-seeking when …
[HTML][HTML] Functional brain responses to emotional faces after three to five weeks of intake of escitalopram in healthy individuals: a double-blind, placebo-controlled …
Short-term intake of selective serotonin reuptake inhibitors (SSRIs) modulates threat-related
amygdala responses in healthy individuals. However, how SSRI intake over a clinically …
amygdala responses in healthy individuals. However, how SSRI intake over a clinically …
[HTML][HTML] Long-term effects of early treatment with SSRIs on cognition and brain development in individuals with 22q11. 2 deletion syndrome
Cognitive deficits in individuals at risk of psychosis represent a significant challenge for
research, as current strategies for symptomatic treatment are often ineffective. Recent …
research, as current strategies for symptomatic treatment are often ineffective. Recent …