[HTML][HTML] Selective neuronal vulnerability to oxidative stress in the brain
X Wang, EK Michaelis - Frontiers in aging neuroscience, 2010 - frontiersin.org
Oxidative stress (OS), caused by the imbalance between the generation and detoxification of
reactive oxygen and nitrogen species (ROS/RNS), plays an important role in brain aging …
reactive oxygen and nitrogen species (ROS/RNS), plays an important role in brain aging …
[HTML][HTML] Integration of cellular bioenergetics with mitochondrial quality control and autophagy
BG Hill, GA Benavides, JR Lancaster Jr… - Biological …, 2012 - degruyter.com
Bioenergetic dysfunction is emerging as a cornerstone for establishing a framework for
understanding the pathophysiology of cardiovascular disease, diabetes, cancer and …
understanding the pathophysiology of cardiovascular disease, diabetes, cancer and …
Good stress, bad stress and oxidative stress: insights from anticipatory cortisol reactivity
Chronic psychological stress appears to accelerate biological aging, and oxidative damage
is an important potential mediator of this process. However, the mechanisms by which …
is an important potential mediator of this process. However, the mechanisms by which …
[HTML][HTML] Interplay between oxidant species and energy metabolism
It has long been recognized that energy metabolism is linked to the production of reactive
oxygen species (ROS) and critical enzymes allied to metabolic pathways can be affected by …
oxygen species (ROS) and critical enzymes allied to metabolic pathways can be affected by …
Lipid peroxidation: physiological levels and dual biological effects
E Niki - Free Radical Biology and Medicine, 2009 - Elsevier
Lipid peroxidation (LPO) has been shown to induce disturbance of membrane organization
and functional loss and modification of proteins and DNA bases, and it has been implicated …
and functional loss and modification of proteins and DNA bases, and it has been implicated …
Update on uses and properties of citrus flavonoids: new findings in anticancer, cardiovascular, and anti-inflammatory activity
O Benavente-Garcia, J Castillo - Journal of agricultural and food …, 2008 - ACS Publications
Significantly, much of the activity of Citrus flavonoids appears to impact blood and
microvascular endothelial cells, and it is not surprising that the two main areas of research …
microvascular endothelial cells, and it is not surprising that the two main areas of research …
Assessing cardiac metabolism: a scientific statement from the American Heart Association
H Taegtmeyer, ME Young, GD Lopaschuk… - Circulation …, 2016 - Am Heart Assoc
In a complex system of interrelated reactions, the heart converts chemical energy to
mechanical energy. Energy transfer is achieved through coordinated activation of enzymes …
mechanical energy. Energy transfer is achieved through coordinated activation of enzymes …
Redox control of inflammation in macrophages
B Brüne, N Dehne, N Grossmann, M Jung… - Antioxidants & redox …, 2013 - liebertpub.com
Macrophages are present throughout the human body, constitute important immune effector
cells, and have variable roles in a great number of pathological, but also physiological …
cells, and have variable roles in a great number of pathological, but also physiological …
Nitric oxide in liver diseases
Y Iwakiri, MY Kim - Trends in Pharmacological sciences, 2015 - cell.com
Nitric oxide (NO) and its derivatives play important roles in the physiology and
pathophysiology of the liver. Despite its diverse and complicated roles, certain patterns of …
pathophysiology of the liver. Despite its diverse and complicated roles, certain patterns of …
Assessing bioenergetic function in response to oxidative stress by metabolic profiling
BP Dranka, GA Benavides, AR Diers… - Free Radical Biology …, 2011 - Elsevier
It is now clear that mitochondria are an important target for oxidative stress in a broad range
of pathologies, including cardiovascular disease, diabetes, neurodegeneration, and cancer …
of pathologies, including cardiovascular disease, diabetes, neurodegeneration, and cancer …