Accurate and timely diagnosis of primary immunodeficiencies (PID) is an ongoing effort.
Individuals with PID can be severely impacted by their disease and many experience …

In contrast to reports made early in the pandemic, we show XLA patients remain susceptible
to severe disease. Persistent infection was common and is likely to carry a significant …

CVID patients have an increased susceptibility to vaccine-preventable infections. The
question on the potential benefits of immunization of CVID patients against SARS-CoV-2 …

Despite the growing recognition of a potentially significant respiratory syncytial virus (RSV)
disease burden in adults, relevant evidence in the United Kingdom (UK) is limited. This …

Bacterial respiratory tract infections are the hallmark of primary antibody deficiencies
(PADs). Because they are also among the most common infections in healthy individuals …

Introduction Primary antibody deficiencies (PAD) are inborn defects of the immune system
that result in increased susceptibility to infections. Despite the reduced response to …

Primary immunodeficiency diseases (PIDs) are uncommon in adults; however,
immunoglobulin G subclass deficiency (IGGSCD) is often found in a subset of adult patients …

Background Patients with antibody deficiency suffer chronic respiratory symptoms, recurrent
exacerbations, and progressive airways disease despite systemic replacement of IgG. Little …

Individuals with primary immunodeficiency (PIDD) experience not only infectious
complications but also immune dysregulation leading to autoimmunity, inflammation, and …

Background Antibody-deficient patients are at high risk of respiratory tract infections. Many
therefore receive antibiotic prophylaxis and have access to antibiotics for self-administration …