Cyclodextrin-based ocular drug delivery systems: A comprehensive review
Q Wang, A Zhang, L Zhu, X Yang, G Fang… - Coordination Chemistry …, 2023 - Elsevier
Cyclodextrin (CD), a class of cyclic oligosaccharides with an external hydrophilic surface
and a central hydrophobic cavity is recognized as a promising pharmaceutical excipient due …
and a central hydrophobic cavity is recognized as a promising pharmaceutical excipient due …
Cyclodextrin complexes: Perspective from drug delivery and formulation
Cyclodextrins (CDs) have been widely investigated as a unique pharmaceutical excipient for
past few decades and is still explored for new applications. They are highly versatile …
past few decades and is still explored for new applications. They are highly versatile …
Main applications of cyclodextrins in the food industry as the compounds of choice to form host–guest complexes
A Gonzalez Pereira, M Carpena… - International Journal of …, 2021 - mdpi.com
Cyclodextrins (CDs) are cyclic oligomers broadly used in food manufacturing as food
additives for different purposes, eg, to improve sensorial qualities, shelf life, and …
additives for different purposes, eg, to improve sensorial qualities, shelf life, and …
Recent advances in the redox-responsive drug delivery nanoplatforms: A chemical structure and physical property perspective
S Mollazadeh, M Mackiewicz… - Materials Science and …, 2021 - Elsevier
Poor water solubility, off-target toxicity, and small therapeutic window are among major
obstacles for the development of drug products. Redox-responsive drug delivery …
obstacles for the development of drug products. Redox-responsive drug delivery …
Resveratrol encapsulation: Designing delivery systems to overcome solubility, stability and bioavailability issues
G Davidov-Pardo, DJ McClements - Trends in food science & technology, 2014 - Elsevier
Highlights•Resveratrol is a polyphenol that exhibits beneficial health effects.•Instability,
hydrophobicity and low bioavailability limit resveratrol use.•Encapsulation can be used to …
hydrophobicity and low bioavailability limit resveratrol use.•Encapsulation can be used to …
Getting drugs across biological barriers
The delivery of drugs to a target site frequently involves crossing biological barriers. The
degree and nature of the impediment to flux, as well as the potential approaches to …
degree and nature of the impediment to flux, as well as the potential approaches to …
Electrospinning of dexamethasone/cyclodextrin inclusion complex polymer fibers for dental pulp therapy
Abstract Beta-cyclodextrin (β-CD) is an oligosaccharide commonly used to improve the
aqueous solubility of lipophilic drugs (eg, dexamethasone, DEX). Here we present the …
aqueous solubility of lipophilic drugs (eg, dexamethasone, DEX). Here we present the …
Supramolecular cyclodextrin complex: Diversity, safety, and applications in ocular therapeutics
P Chaudhari, VM Ghate, SA Lewis - Experimental Eye Research, 2019 - Elsevier
Abstract Approximately 30–70% of the existing and new chemical entities exhibit poor
aqueous solubility. For topical ocular delivery, drug molecules need to possess both …
aqueous solubility. For topical ocular delivery, drug molecules need to possess both …
Divinyl sulfone cross-linked cyclodextrin-based polymeric materials: Synthesis and applications as sorbents and encapsulating agents
J Morales-Sanfrutos, FJ Lopez-Jaramillo… - Molecules, 2015 - mdpi.com
The aim of this study was to evaluate the crosslinking abilities of divinyl sulfone (DVS) for the
preparation of novel water-insoluble cyclodextrin-based polymers (CDPs) capable of …
preparation of novel water-insoluble cyclodextrin-based polymers (CDPs) capable of …
Synergetic skin targeting effect of hydroxypropyl-β-cyclodextrin combined with microemulsion for ketoconazole
J Che, Z Wu, W Shao, P Guo, Y Lin, W Pan… - European Journal of …, 2015 - Elsevier
The objective was to develop a ternary skin targeting system for ketoconazole (KET) using a
combined strategy of microemulsion (ME) and cyclodextrin (HP-β-CD), ie, KET-CD-ME …
combined strategy of microemulsion (ME) and cyclodextrin (HP-β-CD), ie, KET-CD-ME …