Cyclodextrin (CD), a class of cyclic oligosaccharides with an external hydrophilic surface
and a central hydrophobic cavity is recognized as a promising pharmaceutical excipient due …

Cyclodextrins (CDs) have been widely investigated as a unique pharmaceutical excipient for
past few decades and is still explored for new applications. They are highly versatile …

Cyclodextrins (CDs) are cyclic oligomers broadly used in food manufacturing as food
additives for different purposes, eg, to improve sensorial qualities, shelf life, and …

Poor water solubility, off-target toxicity, and small therapeutic window are among major
obstacles for the development of drug products. Redox-responsive drug delivery …

Highlights•Resveratrol is a polyphenol that exhibits beneficial health effects.•Instability,
hydrophobicity and low bioavailability limit resveratrol use.•Encapsulation can be used to …

The delivery of drugs to a target site frequently involves crossing biological barriers. The
degree and nature of the impediment to flux, as well as the potential approaches to …

Abstract Beta-cyclodextrin (β-CD) is an oligosaccharide commonly used to improve the
aqueous solubility of lipophilic drugs (eg, dexamethasone, DEX). Here we present the …

Abstract Approximately 30–70% of the existing and new chemical entities exhibit poor
aqueous solubility. For topical ocular delivery, drug molecules need to possess both …

The aim of this study was to evaluate the crosslinking abilities of divinyl sulfone (DVS) for the
preparation of novel water-insoluble cyclodextrin-based polymers (CDPs) capable of …

The objective was to develop a ternary skin targeting system for ketoconazole (KET) using a
combined strategy of microemulsion (ME) and cyclodextrin (HP-β-CD), ie, KET-CD-ME …