Hypes, hopes, and the way forward for microalgal biotechnology

MJ Barbosa, M Janssen, C Südfeld, S D'Adamo… - Trends in …, 2023 - cell.com
The urge for food security and sustainability has advanced the field of microalgal
biotechnology. Microalgae are microorganisms able to grow using (sun) light, fertilizers …

Mixotrophy, a more promising culture mode: Multi-faceted elaboration of carbon and energy metabolism mechanisms to optimize microalgae culture

S Shan, AY Manyakhin, C Wang, B Ge, J Han… - Bioresource …, 2023 - Elsevier
Some mixotrophic microalgae appear to exceed the sum of photoautotrophy and
heterotrophy in terms of biomass production. This paper mainly reviews the carbon and …

The next-generation DNA vaccine platforms and delivery systems: Advances, challenges and prospects

B Lu, JM Lim, B Yu, S Song, P Neeli… - Frontiers in …, 2024 - frontiersin.org
Vaccines have proven effective in the treatment and prevention of numerous diseases.
However, traditional attenuated and inactivated vaccines suffer from certain drawbacks such …

Efficacy of a microalgal feed additive in commercial honey bee colonies used for crop pollination

A McMenamin, M Weiss, W Meikle… - … Agricultural Science & …, 2023 - ACS Publications
Honey bees are experiencing nutritional deficiencies related to intensive agriculture and
climate change, posing major threats to the ecosystem services they provide. Colonies …

Emerging technologies for advancing microalgal photosynthesis and metabolism toward sustainable production

J Hu, W Meng, Y Su, C Qian, W Fu - Frontiers in Marine Science, 2023 - frontiersin.org
Microalgae are unicellular photosynthetic microorganisms that play a vital role in primary
production and have diverse applications in various industries. They have high …

Research hotspots and trends in discovery of anticancer agents from algae: A 20-year bibliometric and visualized analysis based on Web of Science and CiteSpace

K Gao, M Zhang, L Li, M Yang, Q Zheng, Q Liu, R Ning… - Algal Research, 2023 - Elsevier
In recent years, more and more metabolites with anticancer activity in algae have been
isolated and identified, which are promising candidates for cancer therapy. In this work, a …

The red alga Porphyridium as a host for molecular farming: Efficient production of immunologically active hepatitis C virus glycoprotein

A Hammel, LM Cucos, I Caras… - Proceedings of the …, 2024 - National Acad Sciences
Microalgae are promising production platforms for the cost-effective production of
recombinant proteins. We have recently established that the red alga Porphyridium …

Identification, characterization, and engineering of glycosylation in thrombolytics

M Toul, V Slonkova, J Mican, A Urminsky… - Biotechnology …, 2023 - Elsevier
Cardiovascular diseases, such as myocardial infarction, ischemic stroke, and pulmonary
embolism, are the most common causes of disability and death worldwide. Blood clot …

Genetic-engineered Schizochytrium sp. expressing a multiepitopic protein based on Vibrio parahaemolyticus toxins triggers immune responses in mice

E Trujillo, R Villegas-Zagal, A Ramos-Vega… - Algal Research, 2024 - Elsevier
Vibrio parahaemolyticus is a bacterium that naturally occurs in coastal waters and can
multiply in warmer temperatures. Infection with these bacteria can inflict acute gastroenteritis …

[HTML][HTML] Biomanufacturing of glycosylated antibodies: Challenges, solutions, and future prospects

KK Dubey, A Kumar, A Baldia, D Rajput… - Biotechnology …, 2023 - Elsevier
Traditionally, recombinant protein production has been done in several expression hosts of
bacteria, fungi, and majorly CHO (Chinese Hamster Ovary) cells; few have high production …