Repairing large bone defects caused by severe trauma or tumor resection remains one of
the major challenges in orthopedics and maxillofacial surgery. A promising therapeutic …

Despite many decades of research, the allometric scaling of metabolic rates (MRs) remains
poorly understood. Here, we argue that scaling exponents of these allometries do not …

The relationships between metabolic rate, body temperature (Tb), body composition and
ageing are complex, and not fully resolved. In particular, Tb and metabolic rate often change …

Scaling laws relating body mass to species characteristics are among the most universal
quantitative patterns in biology. Within major taxonomic groups, the 4 key ecological …

Life‐history theory concerns the trade‐offs that mold the patterns of investment by animals
between reproduction, growth, and survival. It is widely recognized that physiology plays a …

Calorie restriction (CR) is the most potent, non-pharmacological intervention to support
metabolic health. The effects of calorie restriction exceed weight loss. Consistent throughout …

Comparative studies of aging are often difficult to interpret because of the different factors
that tend to correlate with longevity. We used the AnAge database to study these factors …

The study of energy expenditure (EE) has deep roots in understanding aging and lifespan in
all species. In humans, total EE decreases substantially in advanced age resulting from …

Beat perception and synchronization within 120 to 140 beats/min (BPM) are common in
humans and frequently used in music composition. Why beat synchronization is uncommon …

Several articles describe highly accurate age estimation methods based on human DNA-
methylation data. It is not yet known whether similar epigenetic aging clocks can be …