When to Think About Other Borreliae:: hard Tick Relapsing Fever (Borrelia miyamotoi), Borrelia mayonii, and Beyond

KG Rodino, BS Pritt - Infectious Disease Clinics, 2022 - id.theclinics.com
Several hard tick-transmitted Borrelia species cause human disease. While Borrelia
burgdorferi sensu stricto (hereafter referred to as B. burgdorferi) is the most common cause …

[HTML][HTML] Detection of Borrelia burgdorferi sensu lato species in host-seeking Ixodes species ticks in the United States

LM Osikowicz, MR Rizzo, A Hojgaard, SE Maes… - Ticks and tick-borne …, 2024 - Elsevier
Lyme disease is the most commonly reported vector-borne disease in the United States and
is transmitted by Ixodes scapularis in the eastern US and I. pacificus in the west. The …

[HTML][HTML] A bioinformatics pipeline for a tick pathogen surveillance multiplex amplicon sequencing assay

LM Osikowicz, A Hojgaard, S Maes, RJ Eisen… - Ticks and tick-borne …, 2023 - Elsevier
Abstract The Centers for Disease Control and Prevention's national tick and tick-borne
pathogen surveillance program collects information to better understand the regional …

[HTML][HTML] Development of a quadruplex PCR amplicon next generation sequencing assay for detection and differentiation of Bartonella spp.

Y Bai, LM Osikowicz, A Hojgaard, RJ Eisen - Frontiers in Microbiology, 2023 - frontiersin.org
The genus Bartonella includes a group of species that are associated with a wide range of
mammalian species, including human. It is challenging to detect all Bartonella species using …

Using next generation sequencing for molecular detection and differentiation of Anaplasma phagocytophilum variants from host seeking Ixodes scapularis ticks in the …

A Hojgaard, LM Osikowicz, MF Rizzo, BN Ayres… - Ticks and Tick-borne …, 2022 - Elsevier
Anaplasmosis is increasingly common in the United States, with cases being reported over
an expanding geographic area. To monitor for changes in risk of human infection, the US …

[HTML][HTML] Analysis of variable major protein antigenic variation in the relapsing fever spirochete, Borrelia miyamotoi, in response to polyclonal antibody selection …

RD Gilmore, BA Armstrong, KS Brandt, TJ Van Gundy… - PLoS …, 2023 - journals.plos.org
Borrelia miyamotoi is a tick-transmitted spirochete that is genetically grouped with relapsing
fever Borrelia and possesses multiple archived pseudogenes that encode variable major …

[HTML][HTML] A next generation sequencing assay combining Ixodes species identification with pathogen detection to support tick surveillance efforts in the United States

LM Osikowicz, SE Maes, RJ Eisen… - Ticks and Tick-borne …, 2024 - Elsevier
The burden of tick-borne diseases continues to increase in the United States. Tick
surveillance has been implemented to monitor changes in the distribution and prevalence of …

Ticks and tick-borne microbes identified through passive and active surveillance in Alaska

MB Hahn, A Hojgaard, G Disler… - Journal of Medical …, 2023 - academic.oup.com
Rapid environmental change in Alaska and other regions of the Arctic and sub-Arctic has
raised concerns about increasing human exposure to ticks and the pathogens they carry …

Detection of Genetic Variability in Borrelia miyamotoi (Spirochaetales: Spirochaetaceae) Between and Within the Eastern and Western United States

A Hojgaard, LM Osikowicz, S Maes… - Journal of Medical …, 2021 - academic.oup.com
Borrelia miyamotoi is a hard tick-associated relapsing fever spirochete that is geographically
widespread in Ixodes spp.(Acari: Ixodidae) ticks, but typically occurs at low prevalence …

[HTML][HTML] Geographic variation in the distribution of Anaplasma phagocytophilum variants in host-seeking Ixodes scapularis nymphs and adults in the eastern United …

A Hojgaard, E Foster, SE Maes, LM Osikowicz… - Ticks and Tick-borne …, 2024 - Elsevier
Human anaplasmosis cases, caused by Anaplasma phagocytophilum, are increasing in the
United States. This trend is explained, in part, by expansion in the geographic range of the …