Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT)
conducted a revision of the 2009 guidelines by updating the evidence and …

Essential elements are very important for the proper functioning of the human body. They
are required for fundamental life processes such as cell division and differentiation and …

Abstract Systems pharmacology is an emerging field that integrates systems biology and
pharmacology to advance the process of drug discovery, development and the …

Recent studies focused on the pharmacology and feasibility of herbal compounds as a
potential strategy to target a variety of human diseases ranging from metabolic to brain …

Mood disorders are a major public health problem and are associated with considerable
burden of disease, suicides, physical comorbidities, high economic costs, and poor quality of …

ABSTRACT Introduction: Basil (Ocimum basilicum L., OB) is a plant world widely used as a
spice and a typical ingredient of the healthy Mediterranean diet. In traditional medicine, OB …

The term adaptogen was introduced into scientific literature in 1958 to denote substances
that increase the “state of nonspecific resistance” during stress, based on Hans Selye's …

Abstract 20 (S)-protopanaxadiol (PPD) possesses a variety of biological activities, including
antioxidant, antifatigue and anti-inflammatory properties. This study was aimed to investigate …

This invention relates to novel pharmaceutical compositions comprising a therapeutically
effective amount of a slow-release formulation of 5-hydroxytryptophan (5-HTP) and a …

Tryptophan (TRP) contributes to individual immune homeostasis and good condition via
three complex metabolism pathways (5-hydroxytryptamine (5-HT), kynurenine (KP), and gut …