Adjunctive 5-hydroxytryptophan slow-release for treatment-resistant depression: clinical and preclinical rationale

JPR Jacobsen, AD Krystal, KRR Krishnan… - Trends in …, 2016 - cell.com
Serotonin transporter (SERT) inhibitors treat depression by elevating brain extracellular 5-
hydroxytryptamine (5-HT Ext). However, only one-third of patients respond adequately …

[引用][C] O demônio do meio-dia: uma anatomia da depressão

A Solomon - 2014 - Editora Companhia das Letras

Evidence-based recommendations for an optimal prenatal supplement for women in the US, part two: Minerals

JB Adams, JC Sorenson, EL Pollard, JK Kirby… - Nutrients, 2021 - mdpi.com
The levels of many essential minerals decrease during pregnancy if un-supplemented,
including calcium, iron, magnesium, selenium, zinc, and possibly chromium and iodine. Sub …

Ginsenoside 20 (S)-protopanaxadiol attenuates depressive-like behaviour and neuroinflammation in chronic unpredictable mild stress-induced depressive rats

N Jiang, L Jingwei, H Wang, H Huang, Q Wang… - Behavioural Brain …, 2020 - Elsevier
Abstract 20 (S)-protopanaxadiol (PPD) possesses a variety of biological activities, including
antioxidant, antifatigue and anti-inflammatory properties. This study was aimed to investigate …

[PDF][PDF] Депрессии и резистентность

ЮВ Быков, РА Беккер, МК Резников - 2013 - researchgate.net
В современной медицине все меньше остается нозологических единиц, которые,
несмотря на самый современный подход и востребованность их изучения, до сих пор …

Chemical Characterization and DNA Fingerprinting of Griffonia simplicifolia Baill.

I Vigliante, G Mannino, ME Maffei - Molecules, 2019 - mdpi.com
Background: Griffonia simplicifolia Baill.(Caesalpiniaceae) is a medicinal plant whose seeds
are widely used in traditional medicine for their high content of 5-hydroxy-l-tryptophan (5 …

Pharmacology of olive biophenols

HK Obied, PD Prenzler, SH Omar, R Ismael… - Advances in molecular …, 2012 - Elsevier
There are more than 100 different biophenols reported in olive samples. This chapter covers
the chemistry, pharmacodynamics, pharmacokinetics, posology, adverse effects, and …

Antidepressants effects of Rhodiola capsule combined with sertraline for major depressive disorder: A randomized double-blind placebo-controlled clinical trial

L Gao, C Wu, Y Liao, J Wang - Journal of affective disorders, 2020 - Elsevier
Background We performed a proof of concept trial to evaluate relative safety and efficacy of
Rhodiola Capsule for mild to moderate major depressive disorder (MDD). Methods It is a …

The therapeutic potential of diet on immune-related diseases: based on the regulation on tryptophan metabolism

J Lin, D Sun-Waterhouse, C Cui - Critical Reviews in Food Science …, 2022 - Taylor & Francis
Tryptophan (TRP), as an essential amino acid, plays crucial roles in maintaining immune
homeostasis due to its complex metabolism pathway, including the microbial metabolism, 5 …

Synergy and antagonism of active constituents of ADAPT-232 on transcriptional level of metabolic regulation of isolated neuroglial cells

A Panossian, R Hamm, O Kadioglu… - Frontiers in …, 2013 - frontiersin.org
Gene expression profiling was performed on the human neuroglial cell line T98G after
treatment with adaptogen ADAPT-232 and its constituents–extracts of Eleutherococcus …