[HTML][HTML] Progress in the mechanism and targeted drug therapy for COPD

C Wang, J Zhou, J Wang, S Li, A Fukunaga… - … and Targeted Therapy, 2020 - nature.com
Chronic obstructive pulmonary disease (COPD) is emphysema and/or chronic bronchitis
characterised by long-term breathing problems and poor airflow. The prevalence of COPD …

[HTML][HTML] Air pollutants and early origins of respiratory diseases

D Kim, Z Chen, LF Zhou, SX Huang - Chronic diseases and translational …, 2018 - Elsevier
Air pollution is a global health threat and causes millions of human deaths annually. The late
onset of respiratory diseases in children and adults due to prenatal or perinatal exposure to …

[HTML][HTML] Vapors produced by electronic cigarettes and e-juices with flavorings induce toxicity, oxidative stress, and inflammatory response in lung epithelial cells and in …

CA Lerner, IK Sundar, H Yao, J Gerloff, DJ Ossip… - PloS one, 2015 - journals.plos.org
Oxidative stress and inflammatory response are the key events in the pathogenesis of
chronic airway diseases. The consumption of electronic cigarettes (e-cigs) with a variety of e …

[HTML][HTML] Role of diet in chronic obstructive pulmonary disease prevention and treatment

E Scoditti, M Massaro, S Garbarino, DM Toraldo - Nutrients, 2019 - mdpi.com
Chronic obstructive pulmonary disease is one of the leading causes of morbidity and
mortality worldwide and a growing healthcare problem. Identification of modifiable risk …

Oxidative stress and free radicals in COPD–implications and relevance for treatment

W Domej, K Oettl, W Renner - International journal of chronic …, 2014 - Taylor & Francis
Oxidative stress occurs when free radicals and other reactive species overwhelm the
availability of antioxidants. Reactive oxygen species (ROS), reactive nitrogen species, and …

Protein carbonylation as a major hallmark of oxidative damage: update of analytical strategies

M Fedorova, RC Bollineni… - Mass spectrometry …, 2014 - Wiley Online Library
Protein carbonylation, one of the most harmful irreversible oxidative protein modifications, is
considered as a major hallmark of oxidative stress‐related disorders. Protein carbonyl …

[HTML][HTML] Aryl hydrocarbon receptor in oxidative stress as a double agent and its biological and therapeutic significance

AY Grishanova, ML Perepechaeva - International Journal of Molecular …, 2022 - mdpi.com
The aryl hydrocarbon receptor (AhR) has long been implicated in the induction of a battery
of genes involved in the metabolism of xenobiotics and endogenous compounds. AhR is a …

[HTML][HTML] SARS-CoV-2 COVID-19 susceptibility and lung inflammatory storm by smoking and vaping

G Kaur, G Lungarella, I Rahman - Journal of Inflammation, 2020 - Springer
The current pandemic of COVID-19 has caused severe morbidity and mortality across the
globe. People with a smoking history have severe disease outcomes by COVID-19 infection …

[HTML][HTML] SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice

H Yao, S Chung, J Hwang… - The Journal of …, 2012 - Am Soc Clin Investig
Chronic obstructive pulmonary disease/emphysema (COPD/emphysema) is characterized
by chronic inflammation and premature lung aging. Anti-aging sirtuin 1 (SIRT1), a NAD+ …

Mitochondrial transfer of induced pluripotent stem cell–derived mesenchymal stem cells to airway epithelial cells attenuates cigarette smoke–induced damage

X Li, Y Zhang, SC Yeung, Y Liang, X Liang… - American journal of …, 2014 - atsjournals.org
Transplantation of mesenchymal stem cells (MSCs) holds great promise in the repair of
cigarette smoke (CS)-induced lung damage in chronic obstructive pulmonary disease …