[HTML][HTML] Progress in the mechanism and targeted drug therapy for COPD
C Wang, J Zhou, J Wang, S Li, A Fukunaga… - … and Targeted Therapy, 2020 - nature.com
Chronic obstructive pulmonary disease (COPD) is emphysema and/or chronic bronchitis
characterised by long-term breathing problems and poor airflow. The prevalence of COPD …
characterised by long-term breathing problems and poor airflow. The prevalence of COPD …
[HTML][HTML] Air pollutants and early origins of respiratory diseases
Air pollution is a global health threat and causes millions of human deaths annually. The late
onset of respiratory diseases in children and adults due to prenatal or perinatal exposure to …
onset of respiratory diseases in children and adults due to prenatal or perinatal exposure to …
[HTML][HTML] Vapors produced by electronic cigarettes and e-juices with flavorings induce toxicity, oxidative stress, and inflammatory response in lung epithelial cells and in …
Oxidative stress and inflammatory response are the key events in the pathogenesis of
chronic airway diseases. The consumption of electronic cigarettes (e-cigs) with a variety of e …
chronic airway diseases. The consumption of electronic cigarettes (e-cigs) with a variety of e …
[HTML][HTML] Role of diet in chronic obstructive pulmonary disease prevention and treatment
E Scoditti, M Massaro, S Garbarino, DM Toraldo - Nutrients, 2019 - mdpi.com
Chronic obstructive pulmonary disease is one of the leading causes of morbidity and
mortality worldwide and a growing healthcare problem. Identification of modifiable risk …
mortality worldwide and a growing healthcare problem. Identification of modifiable risk …
Oxidative stress and free radicals in COPD–implications and relevance for treatment
W Domej, K Oettl, W Renner - International journal of chronic …, 2014 - Taylor & Francis
Oxidative stress occurs when free radicals and other reactive species overwhelm the
availability of antioxidants. Reactive oxygen species (ROS), reactive nitrogen species, and …
availability of antioxidants. Reactive oxygen species (ROS), reactive nitrogen species, and …
Protein carbonylation as a major hallmark of oxidative damage: update of analytical strategies
M Fedorova, RC Bollineni… - Mass spectrometry …, 2014 - Wiley Online Library
Protein carbonylation, one of the most harmful irreversible oxidative protein modifications, is
considered as a major hallmark of oxidative stress‐related disorders. Protein carbonyl …
considered as a major hallmark of oxidative stress‐related disorders. Protein carbonyl …
[HTML][HTML] Aryl hydrocarbon receptor in oxidative stress as a double agent and its biological and therapeutic significance
AY Grishanova, ML Perepechaeva - International Journal of Molecular …, 2022 - mdpi.com
The aryl hydrocarbon receptor (AhR) has long been implicated in the induction of a battery
of genes involved in the metabolism of xenobiotics and endogenous compounds. AhR is a …
of genes involved in the metabolism of xenobiotics and endogenous compounds. AhR is a …
[HTML][HTML] SARS-CoV-2 COVID-19 susceptibility and lung inflammatory storm by smoking and vaping
The current pandemic of COVID-19 has caused severe morbidity and mortality across the
globe. People with a smoking history have severe disease outcomes by COVID-19 infection …
globe. People with a smoking history have severe disease outcomes by COVID-19 infection …
[HTML][HTML] SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice
H Yao, S Chung, J Hwang… - The Journal of …, 2012 - Am Soc Clin Investig
Chronic obstructive pulmonary disease/emphysema (COPD/emphysema) is characterized
by chronic inflammation and premature lung aging. Anti-aging sirtuin 1 (SIRT1), a NAD+ …
by chronic inflammation and premature lung aging. Anti-aging sirtuin 1 (SIRT1), a NAD+ …
Mitochondrial transfer of induced pluripotent stem cell–derived mesenchymal stem cells to airway epithelial cells attenuates cigarette smoke–induced damage
Transplantation of mesenchymal stem cells (MSCs) holds great promise in the repair of
cigarette smoke (CS)-induced lung damage in chronic obstructive pulmonary disease …
cigarette smoke (CS)-induced lung damage in chronic obstructive pulmonary disease …