[HTML][HTML] The concept of folic acid in health and disease
Y Shulpekova, V Nechaev, S Kardasheva, A Sedova… - Molecules, 2021 - mdpi.com
Folates have a pterine core structure and high metabolic activity due to their ability to accept
electrons and react with O-, S-, N-, C-bounds. Folates play a role as cofactors in essential …
electrons and react with O-, S-, N-, C-bounds. Folates play a role as cofactors in essential …
Advances in lung cancer treatment using nanomedicines
A Sharma, D Shambhwani, S Pandey, J Singh… - ACS …, 2022 - ACS Publications
Carcinoma of the lungs is among the most menacing forms of malignancy and has a poor
prognosis, with a low overall survival rate due to delayed detection and ineffectiveness of …
prognosis, with a low overall survival rate due to delayed detection and ineffectiveness of …
[HTML][HTML] Targeting folate receptor alpha for cancer treatment
Promising targeted treatments and immunotherapy strategies in oncology and
advancements in our understanding of molecular pathways that underpin cancer …
advancements in our understanding of molecular pathways that underpin cancer …
Smart targeting to improve cancer therapeutics
M Morales-Cruz, Y Delgado, B Castillo… - Drug design …, 2019 - Taylor & Francis
Cancer is the second largest cause of death worldwide with the number of new cancer
cases predicted to grow significantly in the next decades. Biotechnology and medicine can …
cases predicted to grow significantly in the next decades. Biotechnology and medicine can …
Folate-displaying exosome mediated cytosolic delivery of siRNA avoiding endosome trapping
Folate (FA) receptor is a cell surface glycoprotein overexpressed on many cancer cells. It is
a high affinity ligand for cancer cell targeting. However, delivery of siRNA directly through …
a high affinity ligand for cancer cell targeting. However, delivery of siRNA directly through …
[HTML][HTML] Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes
Background Survival rates for ovarian cancer remain poor, and monitoring and prediction of
therapeutic response may benefit from additional markers. Ovarian cancers frequently …
therapeutic response may benefit from additional markers. Ovarian cancers frequently …
New folate-grafted chitosan derivative to improve delivery of paclitaxel-loaded solid lipid nanoparticles for lung tumor therapy by inhalation
R Rosiere, M Van Woensel, M Gelbcke… - Molecular …, 2018 - ACS Publications
Inhaled chemotherapy for the treatment of lung tumors requires that drug delivery systems
improve selectivity for cancer cells and tumor penetration and allow sufficient lung …
improve selectivity for cancer cells and tumor penetration and allow sufficient lung …
[HTML][HTML] Targeted oral delivery of paclitaxel using colostrum-derived exosomes
Simple Summary Paclitaxel (PAC) is a widely used antitumor agent in the treatment of
various early-stage and advanced cancers, including lung cancer. While efficacious, solvent …
various early-stage and advanced cancers, including lung cancer. While efficacious, solvent …
Bioadhesive chitosan nanoparticles: dual targeting and pharmacokinetic aspects for advanced lung cancer treatment
The chitosan-folate conjugate was synthesized initially and confirmed by FTIR and NMR
spectroscopic studies. Following, docetaxel (DXL) loaded non-targeted, single receptor and …
spectroscopic studies. Following, docetaxel (DXL) loaded non-targeted, single receptor and …
X‐Ray‐Responsive zeolitic imidazolate framework‐capped nanotherapeutics for cervical cancer‐targeting radiosensitization
Developing radiosensitizers based on the characteristics of the tumor microenvironment can
improve the effectiveness and overcome the bottleneck of cervical cancer radiotherapy …
improve the effectiveness and overcome the bottleneck of cervical cancer radiotherapy …