Circadian rhythms and the molecular clock in cardiovascular biology and disease

S Crnko, BC Du Pré, JPG Sluijter… - Nature Reviews …, 2019 - nature.com
The Earth turns on its axis every 24 h; almost all life on the planet has a mechanism—
circadian rhythmicity—to anticipate the daily changes caused by this rotation. The molecular …

Systemic complications of acromegaly and the impact of the current treatment landscape: an update

MR Gadelha, L Kasuki, DST Lim… - Endocrine reviews, 2019 - academic.oup.com
Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …

Obstructive sleep apnea, hypertension and cardiovascular diseases

C Gonzaga, A Bertolami, M Bertolami… - Journal of human …, 2015 - nature.com
Obstructive sleep apnea (OSA) is characterized by recurrent episodes of partial (hypopnea)
or complete interruption (apnea) in breathing during sleep due to airway collapse in the …

Cardiovascular outcomes in patients with COPD-OSA overlap syndrome: a systematic review and meta-analysis

AJ Shah, E Quek, JS Alqahtani, JR Hurst… - Sleep Medicine …, 2022 - Elsevier
Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnoea (OSA) are
prevalent respiratory conditions that are independently associated with increased …

Consequences of circadian and sleep disturbances for the cardiovascular system

FJ Alibhai, EV Tsimakouridze, CJ Reitz, WG Pyle… - Canadian Journal of …, 2015 - Elsevier
Circadian rhythms play a crucial role in our cardiovascular system. Importantly, there has
been a recent flurry of clinical and experimental studies revealing the profound adverse …

[HTML][HTML] Endothelial dysfunction and cardiovascular risk in obstructive sleep apnea: a review article

M Peracaula, D Torres, P Poyatos, N Luque, E Rojas… - Life, 2022 - mdpi.com
Obstructive sleep apnea (OSA) is a respiratory condition during sleep caused by repeated
pauses in breathing due to upper airway obstruction. It is estimated that OSA affects 30% of …

Moving toward equitable care for sleep apnea in the United States: positive airway pressure adherence thresholds: an official American Thoracic Society policy …

AM May, SR Patel, M Yamauchi, TK Verma… - American journal of …, 2023 - atsjournals.org
Background: Positive airway pressure (PAP) is a highly effective treatment for obstructive
sleep apnea (OSA), but adherence limits its efficacy. In addition, coverage of PAP by CMS …

Impact of Renal Denervation on Patients With Obstructive Sleep Apnea and Resistant Hypertension–Insights From the SYMPLICITY HTN-3 Trial–

K Kario, DL Bhatt, DE Kandzari, S Brar, JM Flack… - Circulation …, 2016 - jstage.jst.go.jp
Background: Obstructive sleep apnea (OSA) is associated with activation of the sympathetic
nervous system, and patients with this condition often experience elevated blood pressure …

The role of ferroptosis and endoplasmic reticulum stress in intermittent hypoxia-induced myocardial injury

J Huang, H Xie, Y Yang, L Chen, T Lin, B Wang… - Sleep and …, 2023 - Springer
Purpose Obstructive sleep apnea (OSA) is related to increased risk of cardiovascular
disease. Ferroptosis is a form of programmed cell death characterized by iron overload and …

[HTML][HTML] Effect of dapagliflozin on obstructive sleep apnea in patients with type 2 diabetes: a preliminary study

Y Tang, Q Sun, XY Bai, YF Zhou, QL Zhou… - Nutrition & Diabetes, 2019 - nature.com
Objective The aim of this case-control study was to assess the efficacy of dapagliflozin
combined with metformin for type-2 diabetes mellitus (T2DM) with obstructive sleep apnea …