Aims/hypothesis Insufficient sleep is increasingly recognised as a major risk factor for the
development of obesity and diabetes, and short-term sleep loss in clinical studies leads to a …

Background Metabolic dysfunction associated with fatty liver disease (MAFLD) is often
correlated with obesity and hyperuricemia. The present study aimed to determine the …

Objective Active acromegaly is subject to sex differences in growth hormone (GH) and
Insulin like growth factor 1 (IGF‐I) patterns as well as clinical features but whether this also …

Background Obesity is a major factor behind insulin resistance. The validity of simple
biochemical surrogate measures to estimate insulin resistance at the fat cell level is unclear …

White adipose tissue (WAT) is a robust energy storage and endocrine organ critical for
maintaining metabolic health as we age. Our aim was to identify cell-specific transcriptional …

Metabolic-associated fatty liver disease (MAFLD) has been identified as risk factor of
incident type 2 diabetes (T2D), but the underlying postprandial mechanisms remain unclear …

Objective Adipose tissue distribution and glucose metabolism differ between men and
women. Few studies have investigated sex differences in adipose tissue insulin resistance …

Although metabolic abnormalities commonly occur in non-obese Asians, their pathogenesis
is not fully understood. Proton magnetic resonance spectroscopy has been used to analyze …

Purpose The degree of adipose tissue insulin resistance increases in obesity, prediabetes
and type 2 diabetes, but whether it associates with prediabetes is unclear. Methods This is a …

Objective To examine whether low-dose flutamide administration to normal-weight women
with polycystic ovary syndrome (PCOS) reduces abdominal fat deposition, attenuates …