On closed-loop brain stimulation systems for improving the quality of life of patients with neurological disorders

AN Belkacem, N Jamil, S Khalid… - Frontiers in human …, 2023 - frontiersin.org
Emerging brain technologies have significantly transformed human life in recent decades.
For instance, the closed-loop brain-computer interface (BCI) is an advanced software …

Therapies to restore consciousness in patients with severe brain injuries: a gap analysis and future directions

BL Edlow, LRD Sanz, L Polizzotto, N Pouratian… - Neurocritical care, 2021 - Springer
Abstract Background/Objective For patients with disorders of consciousness (DoC) and their
families, the search for new therapies has been a source of hope and frustration. Almost all …

Ultrasound in traumatic spinal cord injury: a wide-open field

BY Hwang, D Mampre, AK Ahmed, I Suk… - …, 2021 - journals.lww.com
Traumatic spinal cord injury (SCI) is a common and devastating condition. In the absence of
effective validated therapies, there is an urgent need for novel methods to achieve injury …

Low-intensity pulsed ultrasound stimulation (LIPUS) modulates microglial activation following intracortical microelectrode implantation

F Li, J Gallego, NN Tirko, J Greaser, D Bashe… - Nature …, 2024 - nature.com
Microglia are important players in surveillance and repair of the brain. Implanting an
electrode into the cortex activates microglia, produces an inflammatory cascade, triggers the …

Application of low-intensity ultrasound by opening blood–brain barrier for enhanced brain-targeted drug delivery

Q Li, Z Tang, Y Zhang, T Yuan, B Yuan, L Du… - International Journal of …, 2023 - Elsevier
Brain-targeted drug delivery has been a research hotspot, and substantial amount of related
studies were already translated into standard therapy and put into clinical use. However, low …

Effects of low-intensity transcranial pulsed ultrasound treatment in a model of Alzheimer's disease

N dos Santos Tramontin, PCL Silveira… - Ultrasound in Medicine …, 2021 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disease. One of the main
pathology markers of AD is the beta-amyloid plaques (βA 1–42) created from residues of the …

Ambient air PM2. 5 exposure induces heart injury and cardiac hypertrophy in rats through regulation of miR-208a/b, α/β-MHC, and GATA4

L Bai, Y Zhao, L Zhao, M Zhang, Z Cai… - Environmental …, 2021 - Elsevier
Ambient air fine particulate matter (PM 2.5) may increase cardiovascular disease risks. In
this study, we investigated the miR-208/GATA4/myosin heavy chain (MHC) regulation …

Effect of low intensity transcranial ultrasound (LITUS) on post-traumatic brain edema in Rats: evaluation by isotropic 3-dimensional T2 and multi-TE T2 weighted MRI

T Zheng, J Du, Y Yuan, S Wu, Y Jin, Q Shi… - Frontiers in …, 2020 - frontiersin.org
Background: Brain edema is one of the important factors affecting the prognosis of traumatic
brain injury (TBI). Low-intensity transcranial ultrasound (LITUS) has significant anti-cerebral …

Neuroprotective effects of low-intensity transcranial ultrasound stimulation combined with Baicalin intervention on traumatic brain injury in animals

Y Peng, Y Zhao, Y Huang, X Liu, H Zhang, Z Zhao… - Brain Research …, 2021 - Elsevier
Low-intensity transcranial ultrasound stimulation (LITUS) can improve the inflammatory
reaction after traumatic brain injury (TBI), and Baicalin also has a good protective effect on …

Efeito do tratamento com ultrassom pulsado de baixa intensidade transcraniano sobre parâmetros cerebrais em um modelo de doença de Alzheimer induzida por …

NS Tramontin - 2022 - repositorio.ufsc.br
A doença de Alzheimer (DA) é uma doença neurodegenerativa que mais acomete
indivíduos em idade avançada. Sendo caracterizada por piora cognitiva, bem como perda …