Chronic rhinosinusitis (CRS) is a common clinical syndrome that produces significant
morbidity and costs to our health system. The study of CRS has progressed from an era …

Chronic rhinosinusitis with nasal polyps (CRSwNP) is generally associated with eosinophilic
tissue infiltration linked to type 2 inflammation and characterized by elevated levels of …

Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) characterized by a type 2
immune signature often have severe and recurrent disease. Lower airway conditions such …

Background In the Phase III SYNAPSE study, mepolizumab reduced nasal polyp (NP) size
and nasal obstruction in chronic rhinosinusitis with NP (CRSwNP). Objective To assess the …

Background Patients with severe chronic rhinosinusitis with nasal polyps (CRSwNP) often
require repeat sinus surgery. Mepolizumab reduced the need for sinus surgery in the …

Background Integrated care pathways improve the management of patients with chronic
rhinosinusitis with nasal polyps (CRSwNP). The application of integrated care pathways …

Introduction Chronic rhinosinusitis with nasal polyps (CRSwNP) has a high recurrence rate
after surgery despite the availability of medical treatments. Multiple clinical and biological …

The aim of this study was to evaluate the efficacy of mepolizumab in patients affected by
chronic rhinosinusitis with nasal polyps (CRSwNP) in real-life. A single-center retrospective …

The complex pathophysiology of chronic rhinosinusitis with nasal polyps (CRSwNP)
generates a spectrum of phenotypes with a wide variety of inflammatory states. We enrolled …

Introduction Chronic Rhinosinusitis with nasal polyps (CRSwNP) is a common chronic
disease with a high impact on patients' quality of life. If conservative and surgical guideline …