[HTML][HTML] Neutrophil extracellular traps in airway diseases: Pathological roles and therapeutic implications

A Jo, DW Kim - International Journal of Molecular Sciences, 2023 - mdpi.com
Neutrophils are important effector cells of the innate immune response that fight pathogens
by phagocytosis and degranulation. Neutrophil extracellular traps (NETs) are released into …

[HTML][HTML] Advances in the knowledge of the underlying airway remodeling mechanisms in chronic rhinosinusitis based on the endotypes: a review

K Lee, J Tai, SH Lee, TH Kim - International journal of molecular sciences, 2021 - mdpi.com
Chronic rhinosinusitis (CRS) is a chronic inflammatory condition of the nasal and paranasal
sinus mucosa that affects up to 10% of the population worldwide. CRS is the most …

[HTML][HTML] Pathogenesis of chronic rhinosinusitis with nasal polyp and a prominent T2 endotype

SA Shah, M Kobayashi - Heliyon, 2023 - cell.com
Chronic rhinosinusitis is a heterogenous and multifactorial disease, characterized by
persistent inflammation of the nose and paranasal sinuses, which causes nasal obstruction …

Th2 inflammatory responses in the development of nasal polyps and chronic rhinosinusitis

G Ryu, DW Kim - Current opinion in allergy and clinical …, 2020 - journals.lww.com
There is growing evidence of the role of S. aureus in innate and adaptive immunity, which
contribute to Th2 inflammation in CRSwNP. Innate immunity, including epithelial-derived …

[PDF][PDF] Subepithelial neutrophil infiltration as a predictor of the surgical outcome of chronic rhinosinusitis with nasal polyps

DK Kim, HS Lim, KM Eun, Y Seo, JK Kim, YS Kim… - …, 2021 - researchgate.net
Background: Neutrophils present as major inflammatory cells in refractory chronic
rhinosinusitis with nasal polyps (CRSwNP), regardless of the endotype. However, their role …

[HTML][HTML] Neutrophils as a protagonist and target in chronic rhinosinusitis

H Wang, L Pan, Z Liu - Clinical and experimental …, 2019 - synapse.koreamed.org
Neutrophils have traditionally been acknowledged as the first immune cells that are
recruited to inflamed tissues during acute inflammation. By contrast, their importance in the …

Systematic review of protein biomarkers in adult patients with chronic rhinosinusitis

SA Gokani, A Espehana, AC Pratas… - American Journal of …, 2023 - journals.sagepub.com
Background Chronic rhinosinusitis (CRS) is a heterogeneous condition characterized by
differing inflammatory endotypes. The identification of suitable biomarkers could enable …

[HTML][HTML] Elastase-positive neutrophils are associated with refractoriness of chronic rhinosinusitis with nasal polyps in an Asian population

DK Kim, JY Kim, YE Han, JK Kim… - Allergy, asthma & …, 2020 - synapse.koreamed.org
Purpose Various immune cells, including eosinophils and neutrophils, are known to
contribute to the development of chronic rhinosinusitis with nasal polyps (CRSwNP) …

[HTML][HTML] Chemokine expression-based endotype clustering of chronic rhinosinusitis

U Förster-Ruhrmann, AJ Szczepek… - Journal of personalized …, 2022 - mdpi.com
Chronic rhinosinusitis (CRS) with (CRSwNP) or without nasal polyps (CRSsNP) is a
persistent, heterogeneous inflammatory condition affecting the upper respiratory tract. The …

Epidemiology and aetiology of chronic rhinosinusitis in Asia—A narrative review

J Chee, KW Pang, T Low, DY Wang… - Clinical …, 2023 - Wiley Online Library
Background Despite having a similar prevalence to Western populations, literature on
chronic rhinosinusitis (CRS) in the Asian population is sparse. There is limited data on the …