[HTML][HTML] Panax ginseng and its ginsenosides: Potential candidates for the prevention and treatment of chemotherapy-induced side effects

Y Wan, J Wang, J Xu, F Tang, L Chen, Y Tan… - Journal of ginseng …, 2021 - Elsevier
Chemotherapy-induced side effects affect the quality of life and efficacy of treatment of
cancer patients. Current approaches for treating the side effects of chemotherapy are poorly …

Herb–drug interactions between Panax notoginseng or its biologically active compounds and therapeutic drugs: A comprehensive pharmacodynamic and …

Y Xie, C Wang - Journal of Ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Herbs, along with the use of herb–drug interactions (HDIs)
to combat diseases, are increasing in popularity worldwide. HDIs have two effects: favorable …

[HTML][HTML] Traditional uses, chemical diversity and biological activities of Panax L.(Araliaceae): A review

L Liu, FR Xu, YZ Wang - Journal of ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance Panax L.(Araliaceae) is globally-recognized plant
resource suitable for the globalization of traditional Chinese medicines. It has traditionally …

[HTML][HTML] A narrative review of the pharmacology of ginsenoside compound K

T Liu, L Zhu, L Wang - Annals of Translational Medicine, 2022 - ncbi.nlm.nih.gov
Methods The PubMed database was searched for articles published in English from
February 2008 to December 2021 using related keywords such as “Ginsenoside compound …

Ameliorative effects of ginsenosides on myelosuppression induced by chemotherapy or radiotherapy

M He, N Wang, W Zheng, X Cai, D Qi, Y Zhang… - Journal of …, 2021 - Elsevier
Background and ethnopharmacological relevance: As the major side effect of radiotherapy
or chemotherapy, myelosuppression usually leads to anemia, hemorrhage …

Prevention effect of protopanaxadiol-type saponins saponins and protopanaxatriol-type saponins on myelosuppression mice induced by cyclophosphamide

H Zhang, L Zhang, C Yang, Y Zhang, J Li… - Frontiers in …, 2022 - frontiersin.org
Ginsenosides from ginseng are used as a therapeutic agent for various diseases. They
enhance the immunomodulatory effect in cyclophosphamide (CP)-treated tumor disease …

Micelles modified with a chitosan-derived homing peptide for targeted intracellular delivery of ginsenoside compound K to liver cancer cells

J Zhang, Y Jiang, Y Li, W Li, J Zhou, J Chen… - Carbohydrate …, 2020 - Elsevier
Ginsenoside compound K (CK), a major metabolite of protopanaxadiol ginsenosides,
exhibits significant anticancer activities against various cancer cells. However, CK has poor …

Immunomodulatory effects of (24R)-pseudo-ginsenoside HQ and (24S)-pseudo-ginsenoside HQ on cyclophosphamide-induced immunosuppression and their anti …

Z Qi, L Chen, Z Li, Z Shao, Y Qi, K Gao, S Liu… - International journal of …, 2019 - mdpi.com
(24R)-pseudo-ginsenoside HQ (R-PHQ) and (24S)-pseudo-ginsenoside HQ (S-PHQ) are
the main metabolites of (20S)-ginsenoside Rh2 (Rh2) in vivo. In this study, we found that …

Human Serum Albumin Nanoparticles as a Carrier of 20(S)-Protopanaxadiol via Intramuscular Injection to Alleviate Cyclophosphamide-Induced Myelosuppression

L Liu, B Yang, H Yuan, N Yu, Y Feng… - Molecular …, 2023 - ACS Publications
Myelosuppression is a prevalent and potentially life-threatening side effect during
chemotherapy. As the main active component of ginseng, 20 (S)-protopanaxadiol (PPD) is …

Carbohydrates and ginsenosides in shenmai injection jointly improve hematopoietic function during chemotherapy-induced myelosuppression in mice

S Zhang, Y Mi, T Ye, X Lu, L Liu, J Qian, X Fan - Chinese Medicine, 2022 - Springer
Background Shenmai injection (SMI), a traditional Chinese medicine (TCM) injection
prepared from Red ginseng and Ophiopogon japonicus, is widely used in clinics to treat …