Notoginseng saponins (NS) are the active ingredients in Panax notoginseng (Burk.) FH
Chen (PN). NS can be transformed depending on how the extract is processed …

Myelosuppression is a major adverse effect of chemotherapy. With the increasing number of
cancer patients worldwide, there is a growing interest in therapeutic approaches that reduce …

Background Shenmai injection (SMI), a traditional Chinese medicine (TCM) injection
prepared from Red ginseng and Ophiopogon japonicus, is widely used in clinics to treat …

Abstract Context Ginsenoside compound K (CK) has anti-inflammatory, immunoregulatory,
and myelosuppressive protective effects. Methotrexate (MTX) is widely used in combination …

Aplastic anemia (AA) is characterized as hypoplasia of bone marrow hematopoietic cells
and hematopenia of peripheral blood cells. Though the supplement of exogenous …

Objective: This study aimed to investigate the therapeutic effect of Specnuezhenide on
myelosuppression induced by chemotherapy and clarify its mechanism. Methods: In this …

Megakaryocytes (MKs), a kind of functional hematopoietic stem cell, form platelets to
maintain platelet balance through cell differentiation and maturation. In recent years, the …

Immune disorders have become one of the public health problems and imposes a serious
economic and social burden worldwide. Ginsenosides, the main active constituents of …

Ginseng, the dried root of Panax ginseng, contains ginsenosides and has long been used in
Korea, China, and Japan to treat various symptoms. Many studies on the utility of ginseng …

We herein report the use of a sulfo-based column and hydrophilic interaction
chromatography (HILIC) to separate 14 ginsenosides, namely Rb1, Rb2, Rb3, Rc, Rd, Rf …