UT-A urea transporter protein in heart: increased abundance during uremia, hypertension, and heart failure

R Duchesne, JD Klein, JB Velotta, JJ Doran… - Circulation …, 2001 - Am Heart Assoc
Urea transporters have been cloned from kidney medulla (UT-A) and erythrocytes (UT-B).
We determined whether UT-A proteins could be detected in heart and whether their …

Targeted overexpression of ornithine decarboxylase enhances β-adrenergic agonist-induced cardiac hypertrophy

LM SHANTZ, DJ FEITH, AE PEGG - Biochemical Journal, 2001 - portlandpress.com
These studies were designed to determine the consequences of constitutive overexpression
of ornithine decarboxylase (ODC) in the heart. Induction of ODC is known to occur in …

Increases in ornithine decarboxylase activity in the positive inotropism induced by androgens in isolated left atrium of the rat

C Bordallo, JM Rubı́n, AB Varona, B Cantabrana… - European journal of …, 2001 - Elsevier
It is well established that the intracellular receptors of androgens act as transcription factors
upon their activation by androgen binding. However, a growing number of studies have …

Decrease in myocardial polyamine concentration in rats with myocardial infarction

S Hasegawa, M Nakano, K Hamana, Y Taniguchi… - Life sciences, 1997 - Elsevier
Cardiac polyamines are thought to protect the myocardium against harmful stimuli and to be
regulated by sympathetic nerve activation. In the present study, polyamines concentrations …

Lisinopril reduces left ventricular hypertrophy and cardiac polyamine concentrations without a reduction in left ventricular wall stress in transgenic Tsukuba …

T KAI, K ISHIKAWA - Hypertension Research, 2000 - jstage.jst.go.jp
This experiment was designed to determine how the angiotensin-converting enzyme
inhibitor, lisinopril, acts on left ventricular wall stress and cardiac polyamine concentrations …

[PDF][PDF] Role of putrescine in processes of increased heart contractile activity formation

S Avagyan, A Zilfyan, D Yeramyan, S Nersisyan… - The New Armenian …, 2008 - ysmu.am
The influence of putrescine low concentrations on contractile activity of myocardium in large
and small laboratory animals and possible mechanisms of its direct and/or mediated …

Polyamine metabolism and the hypertrophic heart

LM Shantz, E Giordano - Polyamine Cell Signaling: Physiology …, 2006 - Springer
Cardiac muscle hypertrophy is one of the most important compensatory responses of the
heart to multiple stresses that may be placed on it. If the stress is not relieved, sustained …

Discinesias inducidas por L-DOPA en modelos de enfermedad de Parkinson: implicación de la vía Rho quinasa y sus interacciones con el receptor de (pro) renina y …

A López López - minerva.usc.es
En esta tesis se ha estudiado el papel de la vía Rho quinasa, así como otros componentes
relacionados con la neuroinflamación, como el receptor para (pro) renina y el colesterol en …

The role of adrenoceptors in mechanotransduction

M Weckström, P Tavi, KD Schlüter, HM Piper… - Cardiac …, 2007 - Springer
Adrenoceptors are a large family of seven membrane spanning G-protein coupled receptors
involved in many regulatory processes of the heart. Under conditions of mechanical load to …

The role of angiotension-(1-7) in cardiovascular physiology

JL Grobe - 2006 - search.proquest.com
Heart failure (HF) is a devastating condition that impacts our society emotionally,
physiologically, and fiscally, and it is a growing problem in the United States. Aberrant …