In this paper we investigated how the increase of human estrogen receptor alfa (ERα) gene
expression may affect breast, osteoblast and osteoclast cells. Increase of ERα expression …

Estrogen has received considerable attention as a potential therapeutic agent against
various forms of neurodegenerative diseases including stroke. Experimental data in animal …

The transport of amino acids across the plasma membrane is a process of fundamental
physiological importance. If this process is modified by estrogens and if estrogen receptors …

This laboratory is studying hormonal regulation of tumor suppressor proteins, p53 and
retinoblastoma (pRB). Estrogen receptor and progesterone receptor positive human breast …

Abstract 17β-estradiol (E2), as the main circulating estrogen hormone, plays critical roles in
the physiology and pathophysiology of various tissues. The E2 information is primarily …

Aims Estrogen and progesterone hormone receptor (ER and PR) expression in invasive
breast cancer predicts response to hormone disruptive therapy. Pygopus 2 (h PYGO2) …

We examined the effect of estrogen on the growth of estrogen receptor (ER) stably
transfected cells (Rat1+ ER). 17-β-estradiol (E2, 10 nM) inhibited approximately 35–50% of …

This is the second of three articles which seek to review the relationship between steroid
hormones and cancers of their target organs. This particular text is concerned with …

Breast cancer is the most common cancer among women worldwide and was first shown to
be estrogen-dependent by Beatson in 1896 [1]. Estrogen receptors (ERs) are involved in the …

Endocrine therapies targeting estrogen action are pivotal for the prevention and treatment of
ER-positive breast cancers. Previous studies sought to recreate hormone responsiveness by …