Growth response of breast epithelial cells to estrogen is influenced by EGF

P Briand, BK Lundholt, J Skouv… - Molecular and cellular …, 1999 - Elsevier
Estrogen-induced growth stimulation has not previously been demonstrated in estrogen
receptor (ER) cDNA transfected human cell lines in contrast to breast cancer cell lines …

Both estradiol and tamoxifen decrease proliferation and invasiveness of cancer cells transfected with a mutated estrogen receptor

M Garcia, D Derocq, N Platet, S Bonnet… - The Journal of Steroid …, 1997 - Elsevier
Previous studies have shown that, after wild-type estrogen receptor (ER) transfection in ER-
negative breast cancer cells, estradiol but not tamoxifen prevents growth, invasiveness and …

Characterization of a nontumorigenic human breast epithelial cell line stably transfected with the human estrogen receptor (ER) cDNA

BK Lundholt, MW Madsen, AE Lykkesfeldt… - Molecular and cellular …, 1996 - Elsevier
Estrogens play an important role in breast cancer and the effect of estrogen on growth of
breast cancer cells has been extensively studied. However, only little information is …

Stable over-expression of estrogen receptor-α in ECV304 cells inhibits proliferation and levels of secreted endothelin-1 and vascular endothelial growth factor

SH Ali, AL O'Donnell, S Mohamed, S Mousa… - Molecular and cellular …, 1999 - Elsevier
Studies with mammalian vascular cells have suggested growth inhibitory effects of estrogen
on the vascular wall. To investigate the involvement of estrogen receptor-α (ER) in the …

Development of a flow cytometric assay to study glucocorticoid receptor-mediated gene activation in living cells

BM Necela, JA Cidlowski - Steroids, 2003 - Elsevier
A flow cytometry-based reporter gene assay was developed and utilized to measure
glucocorticoid receptor (GR)-mediated gene activation at the single cell level in living cells …

Activation of G protein-coupled estrogen receptor 1 mimics, but does not mediate, the anti-proliferative action of estradiol on pituitary lactotrophs in primary culture

T Mitsui, M Ishida, M Izawa, J Arita - Endocrine Journal, 2017 - jstage.jst.go.jp
Estrogen binds to nuclear estrogen receptors (ERs) to modulate transcription of target genes
in estrogen-responsive cells. However, recent studies have shown that estrogen also binds …

Estrogen and human breast cancer

YF Hu, IH Russo, J Russo - Endocrine Disruptors–Part II, 2002 - Springer
Breast cancer is the most common neoplastic disease in women worldwide. Development of
breast cancer is profoundly influenced by prolonged exposure to estrogens, but the role of …

Characterization of stably transfected fusion protein GFP‐estrogen receptor‐α in MCF‐7 human breast cancer cells

H Zhao, LL Hart, U Keller, LT Holth… - Journal of cellular …, 2002 - Wiley Online Library
Tagging hormone receptors with the green fluorescent protein (GFP) has increased our
knowledge of ligand dependent sub‐cellular trafficking of hormone receptors. However, the …

High level expression of full-length estrogen receptor in Escherichia coli is facilitated by the uncoupler of oxidative phosphorylation, CCCP

CC Zhang, KA Glenn, MA Kuntz, DJ Shapiro - The Journal of steroid …, 2000 - Elsevier
The expression of high levels of full-length human estrogen receptor α (hERα) in
Escherichia coli has proven difficult. We found that expression of the ER DNA binding …

Establishment of two hormone-responsive mouse mammary carcinoma cell lines derived from a metastatic mammary tumor

A Efeyan, V Fabris, S Merani, C Lanari… - Breast cancer research …, 2004 - Springer
We report the establishment of two mouse mammary cancer cell lines, MC7-2A and MC7-2B
obtained from a mouse mammary carcinoma induced by medroxyprogesterone acetate …