In an effort to prepare effective nonsteroidal antiestrogens without intrinsic estrogenicity and
with greater antagonism than the triarylethylenes (tamoxifen), four (E)-and (Z)-1, 1-dichloro-2 …

Deoxybenzoins (1-(2, 4-dihydroxyphenyl)-2-(4-hydroxyphenyl) ethanone) are possible
precursors or metabolites of isoflavanones which may have xenoestrogenic potential on …

This study addresses the hypothesis that transfection of oligonucleotide mimicking a
negative regulatory sequence of promoter C of estrogen receptor alpha (ERα) gene is …

Estrogen receptor (ER)-negative breast carcinomas are often difficult to treat with
antiestrogens. This work was performed to determine if the re-expression of the human ERα …

The expression of high levels of full-length human estrogen receptor α (hERα) in
Escherichia coli has proven difficult. We found that expression of the ER DNA binding …

2001-03-19 Assigned to REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE
reassignment REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE ASSIGNMENT OF …

The breast is a hormone-responsive organ par excellence. Its development is influenced by
a myriad of hormones and growth factors whose stimulus selectively elicits a response …

It is now known that a very crucial role in breast cancer development, prognosis and
occurrence is played by the estrogen receptor (ER). The steroid hormone estradiol (E2) acts …

The aromatase enzyme is a cytochrome P-450 complex, widely expressed in different
tissues, such as brain, breast, ovary, testes, endometrium skin, bone and fat. In …

Chromatin restricts the accessibility of DNA to regulatory factors; its remodelling over the
regulatory regions contributes to the control of gene expression. An increasing number of …