The multifaceted role of curcumin in advanced nanocurcumin form in the treatment and management of chronic disorders
Curcumin is the primary polyphenol in turmeric's curcuminoid class. It has a wide range of
therapeutic applications, such as anti-inflammatory, antioxidant, antidiabetic …
therapeutic applications, such as anti-inflammatory, antioxidant, antidiabetic …
Drug resistance to targeted therapeutic strategies in non-small cell lung cancer
Rapidly developing molecular biology techniques have been employed to identify cancer
driver genes in specimens from patients with non-small cell lung cancer (NSCLC). Inhibitors …
driver genes in specimens from patients with non-small cell lung cancer (NSCLC). Inhibitors …
[HTML][HTML] Phase 2 study of dabrafenib plus trametinib in patients with BRAF V600E-mutant metastatic NSCLC: updated 5-year survival rates and genomic analysis
D Planchard, B Besse, HJM Groen… - Journal of Thoracic …, 2022 - Elsevier
Introduction Dabrafenib plus trametinib was found to have robust antitumor activity in
patients with BRAF V600E-mutant metastatic NSCLC (mNSCLC). We report updated …
patients with BRAF V600E-mutant metastatic NSCLC (mNSCLC). We report updated …
Clinical effects of immuno-oncology therapy on glioblastoma patients: A systematic review
M Najafi, A Jahanbakhshi, S Finocchi Ghersi… - Brain Sciences, 2023 - mdpi.com
The most prevalent and deadly primary malignant glioma in adults is glioblastoma (GBM),
which has a median survival time of about 15 months. Despite the standard of care for …
which has a median survival time of about 15 months. Despite the standard of care for …
Advances in targeted therapy and immunotherapy for non-small cell lung cancer based on accurate molecular typing
J Dong, B Li, D Lin, Q Zhou, D Huang - Frontiers in pharmacology, 2019 - frontiersin.org
The essence of precision medicine is to achieve the goal of “individualized treatment”
through genotyping of patients and targeted therapy. At present, the pathogenic genes of …
through genotyping of patients and targeted therapy. At present, the pathogenic genes of …
The emerging therapeutic landscape of ALK inhibitors in non-small cell lung cancer
V Gristina, M La Mantia, F Iacono, A Galvano, A Russo… - Pharmaceuticals, 2020 - mdpi.com
The treatment of metastatic non-small cell lung cancer (NSCLC) has undergone a paradigm
shift over the last decade. Better molecular characterization of the disease has led to the …
shift over the last decade. Better molecular characterization of the disease has led to the …
Clinical relevance of targeted therapy and immune-checkpoint inhibition in lung cancer
GM Leone, S Candido, A Lavoro, S Vivarelli, G Gattuso… - Pharmaceutics, 2023 - mdpi.com
Lung cancer (LC) represents the second most diagnosed tumor and the malignancy with the
highest mortality rate. In recent years, tremendous progress has been made in the treatment …
highest mortality rate. In recent years, tremendous progress has been made in the treatment …
EML4‑ALK fusion gene in non‑small cell lung cancer
Y Lei, Y Lei, X Shi, J Wang - Oncology letters, 2022 - spandidos-publications.com
Non‑small cell lung cancer (NSCLC) is a malignant tumor with a high morbidity and mortality
rate that is a threat to human health. With the development of molecular targeted research …
rate that is a threat to human health. With the development of molecular targeted research …
The neuronal tyrosine kinase receptor ligand ALKAL2 mediates persistent pain
M Defaye, MC Iftinca, VM Gadotti… - The Journal of …, 2022 - Am Soc Clin Investig
The anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase known for its oncogenic
potential that is involved in the development of the peripheral and central nervous system …
potential that is involved in the development of the peripheral and central nervous system …
Safety and efficacy of anaplastic lymphoma kinase tyrosine kinase inhibitors in non‑small cell lung cancer
L Wang, W Wang - Oncology reports, 2021 - spandidos-publications.com
Since the discovery of targeted therapy with epidermal growth factor receptor (EGFR),
anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) have been introduced as …
anaplastic lymphoma kinase (ALK) tyrosine kinase inhibitors (TKIs) have been introduced as …