Cancer immune surveillance is essential for the inhibition of carcinogenesis. Malignantly
transformed cells can be recognized by both the innate and adaptive immune systems …

Bladder cancer (BC) is a common type of cancer worldwide. Currently, the gold standard
treatment is transurethral resection of bladder tumor (TUR-Bt) accompanied by intravesical …

Metformin, an oral antidiabetic agent, has been reported to potentiate chemotherapeutic-
induced cytotoxicity. In this study, we investigated the effects and molecular mechanisms of …

Objective: To analyze the expression profile variation of lncRNAs in normal urinary bladder
tissue and urothelial carcinoma of the urinary bladder through microarray technology. The …

Bladder cancer is one of the most frequent malignancies in developed countries and it is
also characterized by a high number of recurrences. Despite this, several authors in the past …

Genetic and epigenetic changes in the mitogen activated protein kinase (MAPK) signaling
render urothelial cancer a potential target for tyrosine kinase inhibitor (TKI) treatment …

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), a member of the
TNF superfamily, has garnered interest as it is relatively non‑toxic to normal cells, but …

Purpose: We investigated the mechanisms underlying cisplatin resistance in human bladder
cancer cells to provide novel molecular targets for the treatment of cisplatin resistant bladder …

Elimination of superfluous or mutated somatic cells is provided by various mechanisms
including apoptosis, and deregulation of apoptotic signaling pathways contributes to …

Clear cell renal cell carcinoma (ccRCC) is the most-prominent tumor type of kidney cancers.
Resistance of renal cell carcinoma (RCC) against tumor therapy is often owing to apoptosis …