Treating pathologies of the inner ear is a major challenge. To date, a wide range of
procedures exists for administering therapeutic agents to the inner ear, with varying degrees …

Hearing impairment is the most common sensory disorder in humans, and yet hardly any
medications are licensed for the treatment of inner ear pathologies. Intricate …

Microtechnologies for inner ear drug delivery : Current Opinion in Otolaryngology & Head and
Neck Surgery Microtechnologies for inner ear drug delivery : Current Opinion in Otolaryngology …

The effective delivery of drugs to the inner ear is still an unmet medical need. Local
controlled drug delivery to this sensory organ is challenging due to its location in the petrous …

Drug delivery to the inner ear is an important and very challenging field. The cochlea is
protected by several barriers that need to be overcome in the drug delivery process. Local …

Cochlear implants containing iridium platinum electrodes are used to transmit electrical
signals into the inner ear of patients suffering from severe or profound deafness without …

The c. 151C> T founder mutation in COCH is a frequent cause of late-onset, dominantly
inherited hearing impairment and vestibular dysfunction (DFNA9) in the Dutch/Belgian …

The aim of this study was to better understand the long term behavior of silicone-based
cochlear implants loaded with dexamethasone: in vitro as well as in vivo (gerbils). This type …

The round window membrane (RWM) is the most common entryway for local drug and gene
delivery into the inner ear, but its permeability can change the treatment outcome. We …

Medicine is a science in constant evolution and full of uncertainty. As William Osler said:'The
greater the ignorance, the greater the dogmatism'. This is especially true for diseases little …