Identification of the role of MCM6 in bladder cancer prognosis, immunotherapy response, and in vitro experimental investigation using multi-omics analysis
J Wang, X Li, S Chen, J Cao, X Fan, H Wang, X Zhang… - Life Sciences, 2023 - Elsevier
Background The tumor-promoting effects of MCM6 in numerous tumors have been widely
revealed, yet its specific role in bladder cancer (BLCA) is still elusive. The objective of this …
revealed, yet its specific role in bladder cancer (BLCA) is still elusive. The objective of this …
[HTML][HTML] The prognosis, chemotherapy and immunotherapy efficacy of the SUMOylation pathway signature and the role of UBA2 in lung adenocarcinoma
L Yu, N Lin, Y Ye, H Zhuang, S Zou, Y Song… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Lung adenocarcinoma (LUAD) is one of the most common malignant tumors worldwide.
Small Ubiquitin-like Modifier (SUMO)-ylation plays a crucial role in tumorigenesis. However …
Small Ubiquitin-like Modifier (SUMO)-ylation plays a crucial role in tumorigenesis. However …
[HTML][HTML] Cathepsin B as a key regulator of ferroptosis in microglia following intracerebral hemorrhage
J Lu, H Li, Z Yu, C Cao, Z Xu, L Peng, JH Zhang… - Neurobiology of …, 2024 - Elsevier
Intracerebral hemorrhage (ICH) is a subtype of stroke marked by elevated mortality and
disability rates. Recently, mounting evidence suggests a significant role of ferroptosis in the …
disability rates. Recently, mounting evidence suggests a significant role of ferroptosis in the …
Identification of BGN positive fibroblasts as a driving factor for colorectal cancer and development of its related prognostic model combined with machine learning
S Hu, Q Xiao, R Gao, J Qin, J Nie, Y Chen, J Lou… - BMC cancer, 2024 - Springer
Background Numerous studies have indicated that cancer-associated fibroblasts (CAFs)
play a crucial role in the progression of colorectal cancer (CRC). However, there are still …
play a crucial role in the progression of colorectal cancer (CRC). However, there are still …
[HTML][HTML] Association between spatial distribution of leukocyte subsets and clinical presentation of head and neck squamous cell carcinoma
C Netzer, V von Arps-Aubert, I Mačinković… - Frontiers in …, 2024 - frontiersin.org
Background Interactions between tumor cells and cells in the microenvironment contribute to
tumor development and metastasis. The spatial arrangement of individual cells in relation to …
tumor development and metastasis. The spatial arrangement of individual cells in relation to …
[HTML][HTML] HES4 is a potential biomarker for bladder cancer: a Mendelian randomization study
Z Tan, X Chen, H Li, Y Huang, S Fu, M Ding… - Journal of …, 2024 - ncbi.nlm.nih.gov
Background: Patients with bladder cancer (BLCA) have a poor prognosis and little progress
has been made in treatment. Therefore, the purpose of this work was to employ Mendelian …
has been made in treatment. Therefore, the purpose of this work was to employ Mendelian …
LncRNA CARMN inhibits abdominal aortic aneurysm formation and vascular smooth muscle cell phenotypic transformation by interacting with SRF
S Liu, H Zhou, D Han, H Song, Y Li, S He, Y Du… - Cellular and Molecular …, 2024 - Springer
Phenotypic transformation of vascular smooth muscle cells (VSMCs) plays a crucial role in
abdominal aortic aneurysm (AAA) formation. CARMN, a highly conserved, VSMC-enriched …
abdominal aortic aneurysm (AAA) formation. CARMN, a highly conserved, VSMC-enriched …
[HTML][HTML] SCInter: A comprehensive single-cell transcriptome integration database for human and mouse
J Zhao, Y Wang, C Feng, M Yin, Y Gao, L Wei… - Computational and …, 2024 - Elsevier
Single-cell RNA sequencing (scRNA-seq), which profiles gene expression at the cellular
level, has effectively explored cell heterogeneity and reconstructed developmental …
level, has effectively explored cell heterogeneity and reconstructed developmental …
Exploring the resistance mechanism of triple-negative breast cancer to paclitaxel through the scRNA-seq analysis
W Gao, L Sun, J Gai, Y Cao, S Zhang - Plos one, 2024 - journals.plos.org
Background The triple negative breast cancer (TNBC) is the most malignant subtype of
breast cancer with high aggressiveness. Although paclitaxel-based chemotherapy scenario …
breast cancer with high aggressiveness. Although paclitaxel-based chemotherapy scenario …
A novel defined programmed cell death related gene signature for predicting the prognosis of serous ovarian cancer
F Zhan, Y Guo, L He - Journal of Ovarian Research, 2024 - Springer
Purpose This study aims to explore the contribution of differentially expressed programmed
cell death genes (DEPCDGs) to the heterogeneity of serous ovarian cancer (SOC) through …
cell death genes (DEPCDGs) to the heterogeneity of serous ovarian cancer (SOC) through …