[HTML][HTML] Natural products can be used in therapeutic management of COVID-19: Probable mechanistic insights

S Ali, M Alam, F Khatoon, U Fatima, AM Elasbali… - Biomedicine & …, 2022 - Elsevier
The unexpected emergence of the new Coronavirus disease (COVID-19) has affected more
than three hundred million individuals and resulted in more than five million deaths …

[HTML][HTML] Ursolic and oleanolic acids: Plant metabolites with neuroprotective potential

E Gudoityte, O Arandarcikaite, I Mazeikiene… - International Journal of …, 2021 - mdpi.com
Ursolic and oleanolic acids are secondary plant metabolites that are known to be involved in
the plant defence system against water loss and pathogens. Nowadays these triterpenoids …

[HTML][HTML] Ursolic acid-based derivatives as potential anti-cancer agents: An update

V Khwaza, OO Oyedeji, BA Aderibigbe - International journal of molecular …, 2020 - mdpi.com
Ursolic acid is a pharmacologically active pentacyclic triterpenoid derived from medicinal
plants, fruit, and vegetables. The pharmacological activities of ursolic acid have been …

[HTML][HTML] In vitro and in vivo biological activities of azulene derivatives with potential applications in medicine

P Bakun, B Czarczynska-Goslinska, T Goslinski… - Medicinal Chemistry …, 2021 - Springer
Azulene is an aromatic hydrocarbon that possesses a unique chemical structure and
interesting biological properties. Azulene derivatives, including guaiazulene or …

Network pharmacology for the identification of phytochemicals in traditional Chinese medicine for COVID-19 that may regulate interleukin-6

W Niu, F Wu, W Cao, Z Wu, YC Chao, F Peng… - Bioscience …, 2021 - portlandpress.com
Objective:´ Three formulas and three medicines,'namely, Jinhua Qinggan Granule, Lianhua
Qingwen Capsule, Xuebijing Injection, Qingfei Paidu Decoction, HuaShi BaiDu Formula …

[HTML][HTML] Biological and pharmacological effects of synthetic saponins

YP Juang, PH Liang - Molecules, 2020 - mdpi.com
Saponins are amphiphilic molecules consisting of carbohydrate and either triterpenoid or
steroid aglycone moieties and are noted for their multiple biological activities—Fungicidal …

[HTML][HTML] Terpenoids as potential geroprotectors

E Proshkina, S Plyusnin, T Babak, E Lashmanova… - Antioxidants, 2020 - mdpi.com
Terpenes and terpenoids are the largest groups of plant secondary metabolites. However,
unlike polyphenols, they are rarely associated with geroprotective properties. Here we …

[HTML][HTML] Ursolic acid: A natural modulator of signaling networks in different cancers

S Zafar, K Khan, A Hafeez, M Irfan, M Armaghan… - Cancer Cell …, 2022 - Springer
Incidence rate of cancer is estimated to increase by 40% in 2030. Furthermore, the
development of resistance against currently available treatment strategies has contributed to …

[HTML][HTML] The ethnobotanical, phytochemistry and pharmacological activities of Psidium guajava L.

EA Ugbogu, O Emmanuel, ME Uche, ED Dike… - Arabian Journal of …, 2022 - Elsevier
Psidium guajava L., commonly known as guava is an important tropical food plant with
diverse medicinal values. In traditional medicine, it is used in the treatment of various …

Isoginkgetin, a potential CDK6 inhibitor, suppresses SLC2A1/GLUT1 enhancer activity to induce AMPK-ULK1-mediated cytotoxic autophagy in hepatocellular …

J Yao, S Tang, C Shi, Y Lin, L Ge, Q Chen, B Ou, D Liu… - Autophagy, 2023 - Taylor & Francis
Isoginkgetin (ISO), a natural biflavonoid, exhibited cytotoxic activity against several types of
cancer cells. However, its effects on hepatocellular carcinoma (HCC) cells and mechanism …