Background Food processing alters diet digestibility and composition, thereby influencing
interactions between host biology, diet, and the gut microbiota. The fecal metabolome offers …

Non-alcoholic steatohepatitis (NASH) has become a global health issue, which poses
additional financial burden to public health care. However, no specific pharmacological …

This study aimed to investigate the effects of miR-145-5p on cardiomyocyte proliferation and
apoptosis, GIGYF1 expression, inflammation, and oxidative stress in rats with myocardial …

Leaves and fruits of lingonberries (Vaccinium vitis-idaea L.) are important raw materials for
the food and health care industries, gaining notoriety as “superfoods”. Cultivation of this …

In ancient times traditional herbs were used to treat different diseases such as stomach
discomfort, toothache, body pain and inflammation, diarrhea, malaria, typhoid, diabetes, and …

Spinal cord injury (SCI) is a disease in which the spinal cord is subjected to various external
forces that cause it to burst, shift, or, in severe cases, injure the spinal tissue, resulting in …

Pentacyclic triterpenoids (PCTs) are a widely distributed class of plant secondary
metabolites. These compounds have high bioactive properties, primarily antitumor and …

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system that is
mainly mediated by pathological T-cells. Experimental autoimmune encephalomyelitis …

Ursolic acid (UA), a natural pentacyclic triterpenoid obtained from fruit and several traditional
Chinese medicinal plants, exhibits anti-inflammatory and hypoglycemic properties …

The pharmacological effectiveness of loquat leaf extract (LE) and its important component,
ursolic acid (UA), in the treatment of diabetes mellitus, has been well established in …