Dysfunctional Mitochondria in Age-related Neurodegeneration: Utility of Melatonin as an Antioxidant Treatment
Mitochondria functionally degrade as neurons age. Degenerative changes cause inefficient
oxidative phosphorylation (OXPHOS) and elevated electron leakage from the electron …
oxidative phosphorylation (OXPHOS) and elevated electron leakage from the electron …
[HTML][HTML] Nanozymes in cancer immunotherapy: metabolic disruption and therapeutic synergy
X Xu, Y Zhang, C Meng, W Zheng, L Wang… - Journal of Materials …, 2024 - pubs.rsc.org
Over the past decade, there has been a growing emphasis on investigating the role of
immunotherapy in cancer treatment. However, it faces challenges such as limited efficacy, a …
immunotherapy in cancer treatment. However, it faces challenges such as limited efficacy, a …
Glutamine metabolic competition drives immunosuppressive reprogramming of intratumour GPR109A+ myeloid cells to promote liver cancer progression
Y Yang, T Pei, C Liu, M Cao, X Hu, J Yuan, F Chen… - Gut, 2024 - gut.bmj.com
Objective The metabolic characteristics of liver cancer drive considerable hurdles to immune
cells function and cancer immunotherapy. However, how metabolic reprograming in the …
cells function and cancer immunotherapy. However, how metabolic reprograming in the …
The pyruvate dehydrogenase complex at the epigenetic crossroads of acetylation and Lactylation
PW Stacpoole, CO Dirain - Molecular Genetics and Metabolism, 2024 - Elsevier
The pyruvate dehydrogenase complex (PDC) is remarkable for its size and structure as well
as for its physiological and pathological importance. Its canonical location is in the …
as for its physiological and pathological importance. Its canonical location is in the …
Role of novel protein acylation modifications in immunity and its related diseases
X Li, T Yu, X Li, X He, B Zhang, Y Yang - Immunology, 2024 - Wiley Online Library
The cross‐regulation of immunity and metabolism is currently a research hotspot in life
sciences and immunology. Metabolic immunology plays an important role in cutting‐edge …
sciences and immunology. Metabolic immunology plays an important role in cutting‐edge …
Recent advances in understanding the immune microenvironment in ovarian cancer
J Chen, L Yang, Y Ma, Y Zhang - Frontiers in Immunology, 2024 - frontiersin.org
The occurrence of ovarian cancer (OC) is a major factor in women's mortality rates. Despite
progress in medical treatments, like new drugs targeting homologous recombination …
progress in medical treatments, like new drugs targeting homologous recombination …
[PDF][PDF] Dysfunctional Mitochondria in Age-related Neurodegeneration: Utility of Melatonin as an Antioxidant TreatmentRunning title: Neural mitochondrial dysfunction …
Dysfunctional Mitochondria in Age-related Neurodegeneration_ Utility of Melatonin as an
Antioxidant TreatmentRunning title_ Neur Page 1 Journal Pre-proof Dysfunctional Mitochondria …
Antioxidant TreatmentRunning title_ Neur Page 1 Journal Pre-proof Dysfunctional Mitochondria …