Background Common mental health problems, such as depression and anxiety, are
estimated to affect up to 15% of the UK population at any one time, and health care systems …

The effects of early‐life trauma and its consequences for the treatment of depression are
reviewed. The prevalence and clinical sequelae of early sexual and physical abuse, neglect …

Depression and anxiety are highly prevalent and comorbid psychiatric traits that cause
considerable burden worldwide. Here we use factor analysis and genomic structural …

Objective: To systematically evaluate the published evidence regarding the characteristics
and effectiveness of disease management programmes. Design: Meta-analysis. Data …

The successful resolution of developmen-tal tasks during childhood has long been
recognized as crucial to adult mental health. Specifically, theorists such as Sigmund Freud …

In this article, we describe an evidence-based stepped care approach to improving the care
of chronic illness in organized health care systems. We review the common principles that …

Context Depression co-occurring with diabetes mellitus is associated with higher health
services costs, suggesting that more effective depression treatment might reduce use of …

Objectives: To conduct a systematic review of the experimental literature in order to identify
better practices in collaborative mental health care in the primary care setting. Methods: A …

PURPOSE: To assess the clinical and economic effects of disease management in patients
with chronic diseases. METHODS: Electronic databases were searched for English …

Loneliness may be regarded as a 'geriatric giant', leading to impaired quality of life, greater
need for institutional care and increased mortality. For the past 30 years, a growing number …