[HTML][HTML] Intrinsic disorder and functional proteomics

P Radivojac, LM Iakoucheva, CJ Oldfield, Z Obradovic… - Biophysical journal, 2007 - cell.com
The recent advances in the prediction of intrinsically disordered proteins and the use of
protein disorder prediction in the fields of molecular biology and bioinformatics are reviewed …

Current state and recent advances in biopharmaceutical production in Escherichia coli, yeasts and mammalian cells

A Berlec, B Štrukelj - Journal of industrial microbiology and …, 2013 - academic.oup.com
Almost all of the 200 or so approved biopharmaceuticals have been produced in one of
three host systems: the bacterium Escherichia coli, yeasts (Saccharomyces cerevisiae …

Breast cancer diagnosis based on feature extraction using a hybrid of K-means and support vector machine algorithms

B Zheng, SW Yoon, SS Lam - Expert Systems with Applications, 2014 - Elsevier
With the development of clinical technologies, different tumor features have been collected
for breast cancer diagnosis. Filtering all the pertinent feature information to support the …

SOLpro: accurate sequence-based prediction of protein solubility

CN Magnan, A Randall, P Baldi - Bioinformatics, 2009 - academic.oup.com
Motivation: Protein insolubility is a major obstacle for many experimental studies. A
sequence-based prediction method able to accurately predict the propensity of a protein to …

High-throughput prediction of protein antigenicity using protein microarray data

CN Magnan, M Zeller, MA Kayala, A Vigil… - …, 2010 - academic.oup.com
Motivation: Discovery of novel protective antigens is fundamental to the development of
vaccines for existing and emerging pathogens. Most computational methods for predicting …

PROSO II–a new method for protein solubility prediction

P Smialowski, G Doose, P Torkler… - The FEBS …, 2012 - Wiley Online Library
Many fields of science and industry depend on efficient production of active protein using
heterologous expression in Escherichia coli. The solubility of proteins upon expression is …

A multi-level intrusion detection method for abnormal network behaviors

SY Ji, BK Jeong, S Choi, DH Jeong - Journal of Network and Computer …, 2016 - Elsevier
Abnormal network traffic analysis has become an increasingly important research topic to
protect computing infrastructures from intruders. Yet, it is challenging to accurately discover …

Clustering-based undersampling with random over sampling examples and support vector machine for imbalanced classification of breast cancer diagnosis

J Zhang, L Chen - Computer Assisted Surgery, 2019 - Taylor & Francis
To overcome the two-class imbalanced classification problem existing in the diagnosis of
breast cancer, a hybrid of Random Over Sampling Example, K-means and Support vector …

Semi-automatic segmentation and classification of pap smear cells

YF Chen, PC Huang, KC Lin, HH Lin… - IEEE Journal of …, 2013 - ieeexplore.ieee.org
Cytologic screening has been widely used for detecting the cervical cancers. In this study, a
semiautomatic PC-based cellular image analysis system was developed for segmenting …

Protein solubility: sequence based prediction and experimental verification

P Smialowski, AJ Martin-Galiano, A Mikolajka… - …, 2007 - academic.oup.com
Motivation: Obtaining soluble proteins in sufficient concentrations is a recurring limiting
factor in various experimental studies. Solubility is an individual trait of proteins which, under …