Endotypes of chronic rhinosinusitis: relationships to disease phenotypes, pathogenesis, clinical findings, and treatment approaches
Chronic rhinosinusitis (CRS) is a common clinical syndrome that produces significant
morbidity and costs to our health system. The study of CRS has progressed from an era …
morbidity and costs to our health system. The study of CRS has progressed from an era …
Mechanisms and pathogenesis of chronic rhinosinusitis
Chronic rhinosinusitis (CRS) is a heterogeneous disease characterized by local
inflammation of the upper airways and is historically divided into 2 main phenotypes: CRS …
inflammation of the upper airways and is historically divided into 2 main phenotypes: CRS …
Th2 inflammatory responses in the development of nasal polyps and chronic rhinosinusitis
G Ryu, DW Kim - Current opinion in allergy and clinical …, 2020 - journals.lww.com
There is growing evidence of the role of S. aureus in innate and adaptive immunity, which
contribute to Th2 inflammation in CRSwNP. Innate immunity, including epithelial-derived …
contribute to Th2 inflammation in CRSwNP. Innate immunity, including epithelial-derived …
[PDF][PDF] Subepithelial neutrophil infiltration as a predictor of the surgical outcome of chronic rhinosinusitis with nasal polyps
DK Kim, HS Lim, KM Eun, Y Seo, JK Kim, YS Kim… - …, 2021 - researchgate.net
Background: Neutrophils present as major inflammatory cells in refractory chronic
rhinosinusitis with nasal polyps (CRSwNP), regardless of the endotype. However, their role …
rhinosinusitis with nasal polyps (CRSwNP), regardless of the endotype. However, their role …
[HTML][HTML] Chinese society of allergy and Chinese society of otorhinolaryngology-head and neck surgery guideline for chronic rhinosinusitis
The current document is based on a consensus reached by a panel of experts from the
Chinese Society of Allergy and the Chinese Society of Otorhinolaryngology-Head and Neck …
Chinese Society of Allergy and the Chinese Society of Otorhinolaryngology-Head and Neck …
Systematic review of protein biomarkers in adult patients with chronic rhinosinusitis
SA Gokani, A Espehana, AC Pratas… - American Journal of …, 2023 - journals.sagepub.com
Background Chronic rhinosinusitis (CRS) is a heterogeneous condition characterized by
differing inflammatory endotypes. The identification of suitable biomarkers could enable …
differing inflammatory endotypes. The identification of suitable biomarkers could enable …
[HTML][HTML] Elastase-positive neutrophils are associated with refractoriness of chronic rhinosinusitis with nasal polyps in an Asian population
DK Kim, JY Kim, YE Han, JK Kim… - Allergy, asthma & …, 2020 - synapse.koreamed.org
Purpose Various immune cells, including eosinophils and neutrophils, are known to
contribute to the development of chronic rhinosinusitis with nasal polyps (CRSwNP) …
contribute to the development of chronic rhinosinusitis with nasal polyps (CRSwNP) …
[HTML][HTML] Staphylococcus aureus Infection and Persistence in Chronic Rhinosinusitis: Focus on Leukocidin ED
D Poddighe, L Vangelista - Toxins, 2020 - mdpi.com
Chronic rhinosinusitis (CRS) is thought to be a multifactorial disease that includes a direct
involvement of bacteria that trigger inflammation and contribute to CRS pathogenesis …
involvement of bacteria that trigger inflammation and contribute to CRS pathogenesis …
[HTML][HTML] Pathogenesis and treatment of chronic rhinosinusitis from the perspective of sinonasal epithelial dysfunction
Y He, Y Fu, Y Wu, T Zhu, H Li - Frontiers in Medicine, 2023 - frontiersin.org
Background Chronic rhinosinusitis (CRS) is a clinical syndrome primarily characterized by
long-term mucosal inflammation of the nasal cavity and sinuses. The pathogenesis of CRS …
long-term mucosal inflammation of the nasal cavity and sinuses. The pathogenesis of CRS …
Chronic rhinosinusitis with nasal polyps in older adults: clinical presentation, pathophysiology, and comorbidity
Abstract Purpose of Review Chronic rhinosinusitis and nasal polyps (CRSwNP) is a
common condition that significantly affects patients' life. This work aims to provide an up-to …
common condition that significantly affects patients' life. This work aims to provide an up-to …