MicroRNA-based diagnosis and therapy
MicroRNAs (miRNAs) are a group of endogenous non-coding RNAs that regulate gene
expression. Alteration in miRNA expression results in changes in the profile of genes …
expression. Alteration in miRNA expression results in changes in the profile of genes …
Circulating microRNAs in cancer: potential and challenge
M Cui, H Wang, X Yao, D Zhang, Y Xie, R Cui… - Frontiers in …, 2019 - frontiersin.org
MicroRNAs (miRNAs) are endogenous non-coding small RNA molecules that can be
secreted into the circulation and exist in remarkably stable forms. Like intercellular miRNAs …
secreted into the circulation and exist in remarkably stable forms. Like intercellular miRNAs …
Evaluation of tumor-derived exosomal miRNA as potential diagnostic biomarkers for early-stage non–small cell lung cancer using next-generation sequencing
X Jin, Y Chen, H Chen, S Fei, D Chen, X Cai, L Liu… - Clinical cancer …, 2017 - AACR
Purpose: To identify tumor-derived exosomal biomarkers that are able to discriminate
between adenocarcinoma and squamous cell carcinoma (SCC) as a noninvasive method in …
between adenocarcinoma and squamous cell carcinoma (SCC) as a noninvasive method in …
miRNAs in lung cancer. A systematic review identifies predictive and prognostic miRNA candidates for precision medicine in lung cancer
S Zhong, H Golpon, P Zardo, J Borlak - Translational Research, 2021 - Elsevier
Lung cancer (LC) is the leading cause of cancer-related death worldwide and miRNAs play
a key role in LC development. To better diagnose LC and to predict drug treatment …
a key role in LC development. To better diagnose LC and to predict drug treatment …
Mir-34: a new weapon against cancer?
The microRNA (miRNA)-34a is a key regulator of tumor suppression. It controls the
expression of a plethora of target proteins involved in cell cycle, differentiation and …
expression of a plethora of target proteins involved in cell cycle, differentiation and …
Circulating microRNAs: Biomarkers of disease
Y Wu, Q Li, R Zhang, X Dai, W Chen, D Xing - Clinica Chimica Acta, 2021 - Elsevier
MicroRNAs are a class of endogenous noncoding single-stranded RNA molecules with
approximately 20–24 nucleotides and are associated with a broad range of biological …
approximately 20–24 nucleotides and are associated with a broad range of biological …
The role of exosomes and miRNAs in drug‐resistance of cancer cells
DH Bach, JY Hong, HJ Park… - International journal of …, 2017 - Wiley Online Library
Chemotherapy, one of the principal approaches for cancer patients, plays a crucial role in
controlling tumor progression. Clinically, tumors reveal a satisfactory response following the …
controlling tumor progression. Clinically, tumors reveal a satisfactory response following the …
Circulating miRNAs: roles in cancer diagnosis, prognosis and therapy
G Cheng - Advanced drug delivery reviews, 2015 - Elsevier
MicroRNAs (miRNAs) belong to a class of small non-coding RNAs that regulate numerous
biological processes by targeting a broad set of messenger RNAs. Recently, miRNAs have …
biological processes by targeting a broad set of messenger RNAs. Recently, miRNAs have …
New concepts in cancer biomarkers: circulating miRNAs in liquid biopsies
The effective and efficient management of cancer patients relies upon early diagnosis and/or
the monitoring of treatment, something that is often difficult to achieve using standard tissue …
the monitoring of treatment, something that is often difficult to achieve using standard tissue …
[HTML][HTML] Non-small cell lung carcinoma (NSCLC): Implications on molecular pathology and advances in early diagnostics and therapeutics
Continuous revision of the histologic and stage-wise classification of lung cancer by the
World Health Organization (WHO) provides the foundation for therapeutic advances by …
World Health Organization (WHO) provides the foundation for therapeutic advances by …