Unwinding circular RNA's role in inflammatory pulmonary diseases

AA Bhat, G Gupta, A Goyal, R Thapa… - Naunyn-Schmiedeberg's …, 2024 - Springer
Circular RNAs (circRNAs) have emerged as pivotal regulators of gene expression and
cellular processes in various physiological and pathological conditions. In recent years …

From LncRNA to metastasis: The MALAT1-EMT axis in cancer progression

R Thapa, O Afzal, M Afzal, G Gupta, AA Bhat… - … -Research and Practice, 2023 - Elsevier
Cancer is a complex disease that causes abnormal genetic changes and unchecked cellular
growth. It also causes a disruption in the normal regulatory processes that leads to the …

The complex role of MEG3: An emerging long non-coding RNA in breast cancer

MS Hussain, AA Majami, H Ali, G Kumar… - … -Research and Practice, 2023 - Elsevier
MEG3, a significant long non-coding RNA (lncRNA), substantially functions in diverse
biological processes, particularly breast cancer (BC) development. Within the imprinting …

Exploring ncRNA-mediated regulation of EGFR signalling in glioblastoma: From mechanisms to therapeutics

R Thapa, M Afzal, A Goyal, G Gupta, AA Bhat… - Life sciences, 2024 - Elsevier
Glioblastoma (GBM) is the most prevalent and deadly primary brain tumor type, with a
discouragingly low survival rate and few effective treatments. An important function of the …

PVT1 lncRNA in lung cancer: A key player in tumorigenesis and therapeutic opportunities

MA Hakami, A Hazazi, FR Khan, O Abdulaziz… - … -Research and Practice, 2023 - Elsevier
The lncRNA PVT1 has emerged as a pivotal component in the intricate landscape of cancer
pathogenesis, particularly in lung cancer. PVT1, situated in the 8q24 chromosomal region …

[HTML][HTML] CircRNAs: Pivotal modulators of TGF-β signalling in cancer pathogenesis

AA Bhat, G Gupta, R Dahiya, R Thapa, A Gahtori… - Non-coding RNA …, 2024 - Elsevier
The intricate molecular landscape of cancer pathogenesis continues to captivate
researchers worldwide, with Circular RNAs (circRNAs) emerging as pivotal players in the …

Polyphenol-loaded nano-carriers for breast cancer therapy: a comprehensive review

AA Bhat, G Gupta, M Afzal, R Thapa, H Ali… - BioNanoScience, 2024 - Springer
Breast cancer remains a significant global health challenge, demanding innovative
therapeutic approaches. Polyphenols, a class of natural compounds widely distributed in …

HOTAIR: A key regulator of the Wnt/β-catenin signaling cascade in cancer progression and treatment

MA Hakami, A Hazazi, O Abdulaziz… - … -Research and Practice, 2023 - Elsevier
The long non-coding RNA (lncRNA) HOTAIR occupies a central position in the complex
domain of cancer biology, particularly concerning its intricate interplay with the Wnt/β …

MicroRNA-21's role in PTEN suppression and PI3K/AKT activation: Implications for cancer biology

HS Chawra, M Agarwal, A Mishra, SS Chandel… - … -Research and Practice, 2024 - Elsevier
Abstract MicroRNA-21 (miR-21) was recognized as a key figure in the intricate web of tumor
biology, with a prominent role in regulating the PTEN tumor suppressor gene and the …

[HTML][HTML] The impact of formaldehyde exposure on lung inflammatory disorders: Insights into asthma, bronchitis, and pulmonary fibrosis

AA Bhat, M Afzal, A Goyal, G Gupta, R Thapa… - Chemico-biological …, 2024 - Elsevier
Lung inflammatory disorders are a major global health burden, impacting millions of people
and raising rates of morbidity and death across many demographic groups. An industrial …